acute kidney injury in diabetes - Introduction Diabetic kidney disease DKD is depression and glucose metabolism diabetes mellitus a wellestablished and major complication of diabetes mellitus DM An estimated 20 to 40 of patients develop DKD in their lifetime12 It is often punctuated by an unpredictable course heralded by a nonlinear fall in glomerular filtration rate GFR compared to other etiologies of chronic kidney disease CKD3 Risk factors for CKD Paralleling this evolution standardized definitions have resulted in a growing appreciation that acute kidney injury AKI is increasing in its incidence rapidly and that people with diabetes are much more likely to develop AKI than people without diabetes Here I propose that AKI should be considered a complication of diabetes alongside Acute Kidney Injury in Diabetes Mellitus PMC PubMed Central PMC Acute kidney injury in diabetes mellitus Epidemiology PubMed Acute kidney injury in diabetic patients A narrative review LWW Acute Kidney Injury A Bona Fide Complication of Diabetes Acute kidney injury AKI and diabetes mellitus DM are public health problems that cause a high socioeconomic burden worldwide In recent years the landscape of AKI etiology has shifted Emerging evidence has demonstrated that DM is an independent risk factor for the onset of AKI while an alternative perspective considers AKI as a bona fide complication of DM When Mogensen Christensen and Vittinghus published their seminal description of the five stages of diabetic nephropathy in 1983 there was no contemporary classification system for AKIAcute insults to the kidney were typically termed acute renal failure and categorized according to the clinical presumption of the site of injury prerenal renal and postrenal Acute kidney injury in diabetic patients A narrative review Acute Kidney Injury A Bona Fide Complication of Diabetes Diabetes Mellitus as a Risk Factor for Progression from Acute Kidney Abstract Diabetes mellitus DM significantly increases the overall morbidity and mortality particularly by elevating the cardiovascular risk The kidneys are severely affected as well partly as a result of intrarenal albumin creatinine ratio american diabetes association athero and arteriosclerosis but also due to noninflammatory glomerular damage diabetic nephropathy Acute kidney injury AKI and diabetes mellitus DM are public health problems that cause a high socioeconomic burden worldwide In recent years the landscape of AKI etiology has shifted Emerging evidence has demonstrated that DM is an independent risk factor for the onset of AKI while an alternative perspective considers AKI as a bona fide Diabetes mellitus DM is the most common cause of chronic kidney disease which leads to endstage renal failure worldwide Glomerular damage renal arteriosclerosis and atherosclerosis are the contributing factors in diabetic patients leading to the progression of kidney damage Diabetes is a distinct risk factor for acute kidney injury Acute kidney injury in diabetes mellitus Epidemiology diagnostic and Acute Kidney Injury and Progressive Diabetic Kidney Disease An Introduction Acute kidney injury AKI is a common complication of critical illness affecting up to 20 of hospitalized patients and almost half of patients in the intensive care unit ICU 1 2 AKI can increase inhospital stay or longterm mortality For example among patients with septic shock the 60day mortality rate of patients with AKI is three to five times that of those without Introduction Diabetic kidney disease DKD is a leading cause of chronic kidney disease CKD with a high risk of dialysis and mortality Given the growing incidence of type 1 and type 2 diabetes in children and adolescents DKD represents a significant public health problem 2 3The pathophysiology of DKD is complex and multifactorial Diabetes is a distinct risk factor for acute kidney injury AKI and AKI is associated with faster advancement of renal disease in patients with diabetes The longterm consequences of AKI include the development of endstage renal disease higher cardiovascular and cerebral events poor quality of life and high morbidity and mortality Acute kidney injury and diabetic kidney disease beda diabetes dan prediabetes in children with acute
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