advance study diabetes ppt - A Summary of the ADVANCE Trial rate of type 1 diabetes Diabetes Care Intensive Blood Glucose Control and Vascular Outcomes in Patients with Recent advances in the treatment of diabetes mellitus PPT SlideShare The Action in Diabetes and Vascular Disease Preterax and Diamicron Modified Release Controlled Evaluation ADVANCE trial assessed the effects of routine bloodpressure lowering and intensive Recent advances in treatment of diabetics mellitus PPT SlideShare Simon R Heller on behalf of the ADVANCE Collaborative Group A Summary of the ADVANCE Trial 1 November 2009 32 suppl2 S357S361 The publication of the UK Prospective Diabetes Study UKPDS in 1998 helped to shape the management of type 2 diabetes in recent years 1 The study demonstrated several points The lower rate of retinal photocoagulation in the ADVANCE trial than in previous studies of diabetes 725 was also reported in another recent trial 26 This low event rate limited the power of the The ADVANCE trial The Lancet Rationale and design of the ADVANCE study a randomised trial of blood pressure lowering and intensive glucose control in highrisk individuals with type 2 diabetes mellitus Action in Diabetes and Vascular Disease PreterAx and DiamicroN ModifiedRelease Controlled Evaluation J Hypertens Suppl 200119S2128 13 ACCORD news conference 14 The ADVANCE Trial results clinical implications and perspectives Recent advances in the treatment of diabetes mellitus include newer drug classes and delivery methods Newer drug classes target the incretin system through GLP1 agonists and DPP4 inhibitors sodiumglucose transporters with SGLT2 inhibitors and amylin signaling with pramlintide Improved insulin formulations include longacting insulins Results from randomized controlled trials have demonstrated conclusively that apa bedanya kencing manis dan diabetes the risk of microvascular complications can be reduced by intensive glycemic control in patients with type 1 12 and type 2 diabetes 35In the Diabetes Control and Complications Trial DCCT there was an 60 reduction in development or progression of diabetic retinopathy nephropathy and neuropathy This document discusses recent advances in the treatment of diabetes mellitus It outlines the evolution of diabetes management from the discovery of insulin in the 1920s to current drug therapies like GLP1 analogs and DPP4 inhibitors Newer potential therapies mentioned include bile acid binders amylin mimetics and stem cell or genebased PPT Summary of ACCORD ADVANCE and VADT Trials PowerPoint Followup of BloodPressure Lowering and Glucose Control in Type 2 Diabetes Download PDF The ADVANCE trial 1 showed that patients with type 2 diabetes who received a fixed combination of 4 mg perindopril and 125 mg indapamide in addition to current therapy had fewer macrovascular events and a lower mortality rate than patients assigned placebo Responsible physicians were allowed to prescribe other treatments Presentation Transcript Summary ofACCORD ADVANCE and VADT Trials ACCORD Action to Control Cardiovascular Risk in Diabetes ADVANCE Action in Diabetes to Prevent Vascular Disease VADT Veterans Administration Diabetes Trail Stephen RithNajarian Diabetes Consultant Bemidji Area IHS ACCORD Study Group NEJM 2008 35825452559 What did the ACCORD ADVANCE and VA Diabetes trials show Effects of Intensive Glucose Lowering in Type 2 Diabetes Milicevic Z Raz I Strojek K et al Hyperglycemia and its effect after acute myocardial infarction on cardiovascular outcomes in patients with Type 2 diabetes skripsi faktor-faktor yang mempengaruhi kepatuhan diet diabetes mellitus HEART2D Study design
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