aetiology of diabetes - Type 2 diabetes should be managed anatomi fisiologi diabetes insipidus with a personalised selfmanagement programme with a focus on diet and lifestyle interventions Glycaemic goals and treatment choices should be individualised Aetiology Type 2 diabetes often presents in people with a background genetic predisposition and is characterised by insulin resistance and Together these factors influence glucose metabolism and the development of diabetes To improve the health of the public we need to understand the causes aetiology of diabetes and to develop ways of preventing the disease We aim to identify how genetic and environmental factors influence the risk of type 2 diabetes and related metabolic Diabetes mellitus DM is a chronic metabolic disorder characterized by persistent hyperglycemia It may be due to impaired insulin secretion resistance to peripheral actions of insulin or both According to the International Diabetes Federation IDF approximately 415 million adults between the ages of 20 to 79 years had diabetes mellitus in 20151 DM is proving to be a global public Diabetes mellitus is taken from the Greek word diabetes meaning siphon to pass through and the Latin word mellitus meaning sweet A review of the history shows that the term diabetes was first used by Apollonius of Memphis around 250 to 300 BC Ancient Greek Indian and Egyptian civilizations discovered the sweet nature of urine in this condition and hence the propagation of the word Globally the number of people with diabetes mellitus has quadrupled in the past three decades and diabetes mellitus is the ninth major cause of death About 1 in 11 adults worldwide now have diabetes mellitus 90 of whom have type 2 diabetes mellitus T2DM Asia is a major area of the rapidly em Understanding the cause of type 2 diabetes Type 2 diabetes in adults Aetiology BMJ Best Practice Type 1 diabetes is due to autoimmune destruction of pancreatic betacells resulting why is there no cure for diabetes type 2 in absolute insulin deficiency Patients often present with markedly elevated blood glucose and are prone to diabetic ketoacidosis in contrast to Type 2 diabetes Autoimmune markers are tested to confirm the diagnosis these include islet cell autoantibodies The global epidemic of type 2 diabetes mellitus T2DM and its complications is a major threat to public health This Review provides an updated view of the global epidemiology of T2DM and the Global aetiology and epidemiology of type 2 diabetes mellitus and its Type 2 Diabetes Etiology Epidemiology Pathogenesis and Springer Type 2 Diabetes StatPearls NCBI Bookshelf Diabetes StatPearls NCBI Bookshelf National Center for Etiology and Pathogenesis of Diabetes Mellitus in Children and Adolescents In this chapter we review the etiology and pathogenesis of Type 1 diabetes mellitus T1DM with particular emphasis on the most common immune mediated form Whereas Type 2 diabetes T2DM appears to be an increasing price paid for worldwide societal affluence there is also evidence worldwide of a rising tide of T1DM The increase in understanding of the pathogenesis of T1DM has made it Global aetiology and epidemiology of type 2 diabetes mellitus Nature Pathogenesis and remission of type 2 diabetes what has the twin cycle Type 2 diabetes has been regarded a complex multifactorial disease that lead to serious health complications including high cardiovascular risks Ley SH Hu FB Global aetiology and epidemiology of type 2 diabetes mellitus and its complications Nat Rev Endocrinol 2018 148898 Google Scholar 3 Iacobucci G Diabetes prescribing in A systematic search in PubMed for English language articles published between Jan 1 1960 and March 1 2024 was carried out Search terms included type 2 diabetes aetiology and heterogeneity Titles and abstracts were used to identify relevant studies Studies were also sought within reference lists of eligible studies Aetiology and Mechanisms of Diabetes and pre diabetes food Related Metabolic Disorders of
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