age infuence in hypoglicemia diabetes - Hypoglycemia from overtreatment is a serious diabetes karna sering janji manis but underrecognized complication among older adults with type 2 diabetes However diabetes treatment is seldom deintensified Koehn DA et al1 The combination of diabetes and old age is a challenging one for clinicians and patients alike As the global prevalence of diabetes continues to surge and as the population Hypoglycemia in Adults Canadian Journal of Diabetes Similarly in a prospective cohort study from 2001 to 2012 the development of severe hypoglycemia was associated with a history of CVD in 624 patients with T2D after adjusting for sex age diabetes duration hypertension HbA1c diabetic complications CV autonomic neuropathy and insulin use Citation 32 Nocturnal hypoglycemia is underdiagnosed in older people with insulin Lacy et al used data collected from the 718 patients with type 1 diabetes mean age 672 years in the Study of Longevity in Diabetes SOLID to perform a crosssectional analysis between cognitive function recent severe hypoglycemia selfreported within the last 12 months and lifetime severe hypoglycemia selfreported event requiring emergency room visit or hospitalization Hypoglycemia in Type 2 Diabetes Electronic medical charts of 640 patients who have type 2 diabetes mellitus and age 60 years were evaluated The mean age SD was 6719 569 years Hypoglycemia incidents with different severity levels were prevalent in 217 n 139 of the patients Evaluation and Management of Adult Hypoglycemic Disorders An Endocrine Aging is by far the strongest known risk factor of diabetes mellitus and CVD 3 In 1958 16 million Americans or 1 of the US population were diagnosed with diabetes mellitus 4 In 2015 an estimated 302 million Americans or 122 of the US population had diabetes mellitus with 72 million or 24 of them unaware of their diabetes mellitus diagnosis 4 Of the 30 million with diabetes With idf 2022 diabetes indonesia increasing age the symptoms of hypoglycemia may become less intense 1213 and the symptom profile is modified 91214In a small British study that compared responses to hypoglycemia in seven five male nondiabetic adults aged 6580 years with six three male younger people aged 2449 years the symptom scores were significantly lower in the older group autonomic and Complications Stratified by Age and Glycemic Control in US Adult Patients With Type 1 Diabetes A RealWorld Study Diabetes Care 2019 42 22202227 PMID 31548241 DOI Iatrogenic hypoglycemia is a major obstacle to achieving glycemic targets in individuals with type 1 or type 2 diabetes mellitus treated with insulin andor insulin secretagogues 13 The risk of severe hypoglycemia in some individuals can necessitate less stringent glycemic goals The frequency and severity of hypoglycemia can negatively impact quality of life 45 in individuals with AgeRelated Changes in Glucose Metabolism Hyperglycemia and How Significant Is Severe Hypoglycemia in Older Adults With Diabetes Prevalence and predictors of hypoglycemia in older outpatients with PDF Hypoglycemia in diabetes An update on ResearchGate Hypoglycemia in Older Adults A Risk Not Fully Recognized CGM is a promising tool to better identify hypoglycemia and adapt diabetes management in this population Key points Around a third of insulintreated older patients with type 2 diabetes experienced hypoglycemia 70 mgdL based on selfmonitoring of blood glucose Given the important overall influence of age T2D duration and geriatric Management of hypoglycemia in older adults with type 2 diabetes Summary of Recommendations 10 Workup for a hypoglycemic disorder 11 We recommend evaluation and management of hypoglycemia only in patients in whom Whipples triadsymptoms signs or both consistent with hypoglycemia a low plasma glucose concentration and resolution of those symptoms or signs after the plasma glucose concentration when to use insulin in type 2 diabetes is raisedis documented 1
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