alpha amylase diabetes - Diabetes mellitus is a metabolic disorder makanan yang sehat untuk penderita diabetes and has become a global disease risk to human health Although various synthetic drugs have been used to treat diabetes efforts to develop novel effective inhibitors against αamylase and αglucosidase are needed The inhibition of alphaglucosidase and alphaamylase enzymes involved in the digestion of carbohydrates can significantly reduce the postprandial increase of blood glucose and therefore can be an important strategy in the management of blood glucose level in type 2 diabetic and borderline patien Alphaamylase as molecular target for treatment of diabetes PubMed Inhibition mechanism of alphaamylase a diabetes target by a Keywords alphaamylase antidiabetic activity postprandial hyperglycemia extract natural compounds type 2 diabetes 1 Introduction Diabetes mellitus is a group of metabolic disorders marked by persistent increases in blood glucose levels This condition is caused by a defect in insulin production insulin function or both factors Alphaamylase as molecular target for treatment of diabetes mellitus A Inhibition mechanism of alphaamylase a diabetes target by a PubMed The alpha αamylase is a calcium metalloenzyme that aids digestion by breaking down polysaccharide molecules into smaller ones such as glucose and maltose In addition the enzyme causes postprandial hyperglycaemia and blood glucose levels to rise αAmylase is a wellknown therapeutic target for the treatment and maintenance of Natural products as alphaamylase and alphaglucosidase inhibitors and Saleh et al 2013 observed significant αglucosidase and αamylase inhibitory in the nhexane fractions of ten plant extracts traditionally used in Iran for diabetes 3334 Our result shows that the n hexane fraction contained the compounds responsible for diabetes drawing images αamylase activity inhibition hence further purification of the extract was New Insights into the Latest Advancement in αAmylase Inhibitors of Foodderived nonphenolic αamylase and αglucosidase inhibitors for Alphaamylase is widely exploited as a drug target for preventing postprandial hyperglycemia in diabetes and other metabolic diseases Inhibition of this enzyme by plantderived pregnanes is not fully understood Herein we used in vitro in silico and in vivo studies to provid Background αamylase and αglucosidase digest the carbohydrates and increase the postprandial glucose level in diabetic patients Inhibiting the activity of these two enzymes can control postprandial hyperglycemia and reduce the risk of developing diabetes Bitter gourd or balsam pear is one of the important medicinal plants used for controlling postprandial hyperglycemia in diabetes AlphaAmylase and AlphaGlucosidase Enzyme Inhibition and Antioxidant Alphaamylase is widely exploited as a drug target for preventing postprandial hyperglycemia in diabetes and other metabolic diseases Inhibition of this enzyme by plantderived pregnanes is not fully understood Herein we used in vitro in silico Alphaamylase inhibition can treat diabetes mellitus ResearchGate In vitro and in vivo αamylase and αglucosidase inhibiting activities This review mainly focused on alpha α amylase as potential biological target for treatment of Diabetes mellitus and summarized all the reported derivatives of different nucleus like The alpha αamylase is a calcium metalloenzyme that aids digestion by breaking down polysaccharide molecules into smaller ones such as glucose and maltose In addition the enzyme causes postprandial hyperglycaemia and blood glucose levels to rise αAmylase is a wellknown therapeutic target for the data diabetes di kalimantan barat 2017 treatment and maintenance of
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