aterosklerosis pada diabetes - Diabetes profoundly affects the pathogenesis of pencegahan diabetes atherosclerosis through various mechanisms Established cardiovascular risk factors are more prevalent in diabetic than in nondiabetic patients Although trials of intensive glycemic control have been somewhat disappointing for decreasing atherogenesis the results of trials with lipidregulating Clinical relationships between diabetes and atherosclerosis are well established The majority of the clinical and experimental data regarding the onset of diabetes complications are associated with atherosclerosis suggesting that the impact of chronic hyperglycaemia might induce damage on vascular homeostasis mainly attributable to the endothelium function The Diabetes MellitusAtherosclerosis Connection The Role of Lipid and The link between diabetes and atherosclerosis PubMed In diabetes evidence of endothelial dysfunction is present Smooth muscle cell proliferation is an important pathologic finding in atherosclerosis This process is stimulated by a platelet mitogen which has been partially characterized The mitogen has not been studied in diabetes Lipid accumulation in the area of the atherosclerotic lesion Introduction Diabetes as a noncommunicable chronic disease NCD represents the major cause of loss of productive life in the European Union EU and premature mortality due to a high incidence of cardiovascular complications cardiovascular diseases CVDs 1 Among the diabetes population 90 are affected by type 2 diabetes mellitus T2DM and 10 by type 1 diabetes mellitus T1DM Pathogenesis of Atherosclerosis in Diabetes Mellitus Atherosclerosis Burdens in Diabetes Mellitus Assessment by PET Imaging Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a common main feature of chronic hyperglycemia that results from defects of insulin secretion insulin action or both Insulin is an important anabolic hormone and its deficiency leads to various metabolic abnormalities in proteins lipids and carbohydrates Atherosclerosis is the most common complication download template ppt presentasi diabetes of diabetes Epidemiologic and pathophysiologic evidence suggest a number of possible reasons for this They include alterations in lipoproteins platelets soluble clotting factors the balance of prostacyclinthromboxane blood pressure regulation and arterial smooth muscle cell metabolism and The link between diabetes and atherosclerosis Lucia La Sala Diabetes and Atherosclerosis Mechanisms and Management 1 Introduction Atherosclerosis is a significant comorbidity in diabetes mellitus and its sequalae acute myocardial infarction stroke and peripheral artery disease are major reasons why diabetes has recently entered the top ten causes of death worldwide However from the literature it is not easy to determine the actual incidence of atherosclerosis in diabetes mellitus DM and how Diabetes and Atherosclerosis an Overview The Diabetes MellitusAtherosclerosis Connection The Role of Lipid and Diabetes and atherosclerosis epidemiology pathophysiology and Context Complications of atherosclerosis cause most morbidity and mortality in patients with diabetes mellitus Despite the frequency and severity of disease proven medical therapy remains incompletely understood and underused Objective To review the epidemiology pathophysiology and medical and invasive treatment of atherosclerosis in patients with diabetes mellitus A simplified scheme of the pathophysiological connection of diabetes mellitus and atherosclerosis Dyslipidemia hyperglycemia and insulin resistance result in a spectrum of physiological changes including the formation of atherogenic lowdensity lipoprotein LDL advanced glycation end products AGE and activation of proinflammatory signaling that impact different cell types of the The link between diabetes and atherosclerosis Oxford Academic Dysfunction of the vascular endothelium is a hallmark of most conditions that are associated with both diabetes and atherosclerosis Although the pathological link between diabetes and atherosclerosis is wellestablished better comprehension of the underlying mechanisms is of utmost importance to identify diabetes boleh makan mangga novel potential molecular targets
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