cac score in type 1 diabetes - Coronary Calcium Score and Prediction of obat diabetes merek AllCause Mortality in Diabetes and metabolic syndrome are major risk factors for coronary heart disease CHD Many patients suffering CHD events are not adequately identified by traditional risk assessment suggesting the need for early detection of subclinical CHD to identify However progression of the calcium a repeat CAC scan provides additional prognostic information of an indication of progression of atherosclerosis In summary the coronary calcium score is a major clinical advance for noninvasively detecting coronary artery disease and managing antiatherosclerotic therapy in type 1 diabetes The Role of a Coronary Artery Calcium Scan in Type 1 Diabetes PMC Findings from a subgroup of MESA aspirinnaïve participants 70 years of age and not at high bleeding risk n 3540 demonstrated that CAC 100 marked a threshold where the number needed to treat NNT was significantly lower than the number needed to harm NNH13 In adults at low risk Data have suggested that a CAC score of 100 or higher predicts cardiovascular risk In a supplement they provided a clinical vignette of a 34yearold man with type 1 diabetes diagnosed at age 10 years with no history of cardiovascular disease or symptoms and no albuminuria TIR is measured as a percentage Blood sugar range goals can vary for each person but a typical target range is between 70 and 180 mgdL For most adults with Type 1 or Type 2 diabetes providers recommend aiming to have a TIR above 70 about 17 hours of a 24hour day In type 2 diabetes mellitus T2DM it remains unclear whether coronary artery calcium CAC provides additional information about cardiovascular disease CVD mortality beyond the Framingham Risk Score FRS factorsA total of 1123 T2DM participants Coronary CT calcium scan Wikipedia Two recent studies found increased low CAC scores in younger populations is unclear Therefore we examined whether progression of CAC over 6 years was increased in participants with low CAC when compared to individuals with zero CAC in the Coronary Artery Calcification in Type 1 Diabetes CACTI The A1C test shows average blood sugar levels over the past 23 months It can help doctors diagnose diabetes and check how well treatment is working Aimshypothesis We sought to assess with type 1 diabetes using data from the Pittsburgh Epidemiology of Diabetes Complications EDC Study Methods The present study examined 292 participants who had at least one CAC measure and were free from CAD at baseline 181 62 had repeat CAC assessments 48 years later and did not develop CAD between the two CAC measures The HRs of incident CAD events were estimated using Cox models in categorised or in appropriately transformed CAC scores The investigators found an increased risk of allcause mortality diabetes mellitus tipo 2 descompensada in patients with diabetes with higher CAC scores with an OR 95 CI of 576 4611039 in CAC 1000 compared with CAC 010 which are similar to our findings and a comparable mortality between patients with diabetes Subhashish Agarwal Amanda J Cox Calcium Score Predicts Cardiovascular Mortality in Diabetes Diabetes Heart Study Diabetes Care 1 April 2013 36 4 972977 httpsdoiorg102337dc121548 In type 2 diabetes mellitus T2DM it remains unclear whether coronary artery calcium CAC provides Coronary Calcium Score Predicts Cardiovascular Mortality in Diabetes Coronary Artery Calcium Score for Longterm Risk Classification The Type 1 Diabetes Composite Score An Innovative Metric for Patient outcomes resulting from optimal type 1 diabetes T1D care have historically focused on driving a single metric hemoglobin A1c Our objectives were to design build and launch an aggregate clinical indicator that comprehensively reflects Coronary Artery Calcium Screening in Persons with Metabolic Syndrome Women with type 1 diabetes were by the atherosclerotic cardiovascular disease ASCVD risk estimator 18 A total of 26 of women with type 1 diabetes had CAC scores greater than zero 11 of women without diabetes had scores greater than zero A low coronary artery calcium score is really different from zero However progression of the calcium a repeat CAC scan provides additional prognostic information of an indication of progression of atherosclerosis In summary the coronary calcium score is a major clinical advance for noninvasively detecting coronary artery disease and managing antiatherosclerotic therapy in type 1 diabetes After 111 mean years of followup score was independently associated with incident CHD in multivariable analyses in those with diabetes HR 130 95 CI 119143 MetS HR 130 95 CI 120141 and neither condition HR 137 95 CI 127147 Onefifth of asymptomatic statinnaïve patients with types 1 diabetes had a positive coronary artery calcium score Positive coronary artery calcium was significantly associated with duration of type 1 diabetes BMI neuropathy and LDLC Steno T1 Risk Engine was superior in identifying In conclusion we found that CAC score is strongly associated with the risk of incident CAD in individuals with type 1 diabetes Inclusion of CAC measures in CAD risk models may lead to improvement in prediction over established risk factors The role of coronary artery calcification testing in incident The wellestablished indications class I low risk based on a family history of early coronary artery disease CAD class IIa and lowrisk patients with diabetes The CAC characteristics of patients are given in Table 2 Among subjects without events half had CAC TCS 0 while all those with chronic and three quarter of the acute events group had CAC Equally the mean CAC score was 10 times higher in the chronic events group than beda diabetes melitus tipe 1 dan 2 in those without events
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