can diabetes cause liver damage - In some cases diabetes can cause diabetes melitus ejaan progressive liver scarring leading to a liver injury known as cirrhosis Diabetes can also speed the progression of liver disease increasing the risk of severe and potentially lifethreatening complications like liver failure or liver cancer In addition there is evidence that having a liver disease can In diabetes mellitus insulin resistance and hyperinsulinaemia cause nonalcoholic fatty liver disease and progress to nonalcoholic steatohepatitis NASH which manifests as inflammation and necrosis Prolonged NASH will lead to liver fibrosis known as cirrhosis and finally hepatocellular carcinomas and endstage liver disease Liver cirrhosis and diabetes Risk factors pathophysiology clinical Abstract Background Liver cirrhosis LC is largely associated with diabetes mellitus DM More than 80 of patients with LC manifest glucose intolerance and about 30 have type 2 DM A particular and yet unrecognized entity is hepatogenous diabetes HD defined as impaired glucose regulation caused by altered liver function following LC The liver is one of the major targets for insulin and its counterregulatory hormones such as glucagonChronic liver disease CLD is often associated with glucose intolerance and diabetes CLD is very prevalent in the general US population and includes 2 of adult Americans 53 million infected with hepatitis B or C 1 and an estimated 31 or more with nonalcoholic fatty liver disease Mechanisms of DiabetesInduced Liver Damage PubMed Central PMC Spectrum of Liver Disease in Type 2 Diabetes and Management of Patients Association between Liver Cirrhosis and Diabetes Mellitus A Review on Type 2 Diabetes and Your Liver Diabetes CDC Centers for Disease Eat a wellbalanced diet To help manage type 2 diabetes and lower your risk of liver disease and other complications your doctor may advise you to make changes in your diet For example they Diabetes How do I help protect my liver Mayo Clinic Type 2 diabetes and liver disease How theyre connected Diabetes and talas untuk diabetes Chronic Liver Disease Etiology and Pitfalls in Monitoring Liver disease is an important cause of death in type 2 diabetes In the populationbased Verona Diabetes Study cirrhosis was the fourth leading cause of death and accounted for 44 of diabetesrelated deathsThe standardized mortality ratio SMR ie the relative rate of an event compared with the background rate for cirrhosis was 252 compared with 134 for cardiovascular disease CVD How to Reduce the Risk of Liver Disease with Type 2 Diabetes Healthline How Type 2 diabetes worsens liver disease One of the main functions of the liver is to maintain healthy blood sugar levels Insulin a hormone made by the pancreas acts as a messenger to alert cells to take up glucose from the blood But in a liver damaged by fat deposits scarring or cirrhosis those cells become less responsive to insulin If you have both conditions and your type 2 diabetes isnt managed well it can make fatty liver disease worse The best ways to prevent fatty liver disease include the following Work with your health care team to manage your blood sugar Lose weight if you need to and try to stay at a healthy weight Diabetes and Liver Disease What Is the Relationship Verywell Health It has been observed that the fatty liver obesity and insulin resistance act as cofactors to cause liver damage134 Spectrum of liver disease in type 2 diabetes and management of patients with diabetes and liver disease Diabetes Care 200730734743 doi 102337dc061539 Google Scholar 4 ElSerag HB Everhart JE Diabetes A buildup of fat and damage in your liver can increase your blood sugar levels NAFLD and type 2 diabetes share many of the same risk factors These include overweight or obesity high blood pressure and high cholesterol Researchers are seeing increasing numbers of people with both type 2 diabetes and nerves diabetes and liver disease
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