central obesity and diabetes - Weight gain and body mass are gestational diabetes in newborns central to the formation and rising incidence of type 1 and type 2 diabetes This literature review will demonstrate the facts that link obesity with insulin resistance and pancreatic βcell dysfunction Diabetes and obesity are chronic disorders that are on the rise worldwide Body mass index has a strong Lipids as the link between central obesity and diabetes perspectives Mechanism linking diabetes mellitus and obesity PMC Genetic Predisposition to Central Obesity and Risk of Type 2 Diabetes Obesity and diabetes are substantial public health concerns that are frequently comorbid Adults with obesity are more likely to develop type 2 diabetes 1 2Cardiometabolic disorders are frequently observed among those who have obesity as measured by body mass index BMI 3 4In recent years more and more researchers are focusing on the cardiometabolic profile of those who are nonobese Background Central obesity is a wellrecognized risk factor for diabetes yet the potential role of lipids in the diabetes risk associated with central obesity remains unclear This study aimed to explore the possible mediating role of 11 lipid parameters highdensity lipoprotein cholesterol HDLC total cholesterol TC nonhighdensity lipoprotein cholesterol NonHDLC lowdensity Obesity and its relation with diabetes and hypertension a cross Obesity and Type 2 Diabetes StatPearls NCBI Bookshelf Indices of central obesity also showed similar linear waist circumference or monotonic waisttohip ratio and waisttoheight ratio associations with type 2 diabetes These positive linear or monotonic associations were confirmed by the analyses of more objective measures of body fat content such as percentage body fat and visceral Normal Weight Central Obesity and its Impact on Type 2 Diabetes The dramatic increase in the global incidence of obesity has been accompanied by an increase in incident type 2 diabetes T2D Anthropometric measures capturing abdominal adiposity such as waist circumference or anime orang gemuk tidur diabetes waisttohip ratio WHR have been related to diabetes risk independent of BMI across various ethnic groups 25Compelling evidence shows that accumulation of visceral fat Anthropometric and adiposity indicators and risk of type 2 diabetes Association between central obesity and incident diabetes mellitus Abdominal obesity is a major risk factor for type 2 diabetes T2D We aimed to examine the association between the genetic predisposition to central obesity assessed by the waisttohip ratio WHR genetic score and T2D riskThe current study included Central obesity was defined using the International Diabetes Federation recommendations of waist circumference 94 cm in men of Caucasian and African ancestry and 80 cm in women of all ethnic backgrounds For East and South Asian men central obesity was defined waist circumference 90 cm We also considered BMI and waist as Excess body weight and obesity are significant risk factors for type 2 diabetes mellitus T2DM Obesity management in patients with T2DM should be implemented according to Guidelines from the American Diabetes Association and the American Obesity Association including lifestyle interventions pharmacologic treatments and surgical indications Leaders at an international consensus conference Genetic Predisposition to Central Obesity and Risk of Type 2 Diabetes Few studies have been conducted on the association between normalweight central obesity and the risk of diabetes mellitus DM Methods 26825 participants from the National Health and Nutrition Examination Survey NHANES were included in our study A weighted multivariate logistic regression model was used to analyze the relationship Normalweight central obesity implications for diabetes mellitus Additionally we employed a doubly robust estimation method to identify the association between central obesity and diabetes Subjects with central obesity were 92 more likely to develop DM HR 165 95CI 112 241 After adjusting for covariates subjects with central obesity had a 72 increased risk of peringkat diabetes indonesia di dunia 2023 developing DM compared with
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