cilostazol pada diabetes - Efficacy and Safety of Adjunctive Cilostazol diabetes tipe 2dengan obesitas to ClopidogrelTreated Results 26 diabetic PAD patients 20 men were recruited Cilostazol improved absolute walking distance at 6 and 24 weeks 864 vs 141 P 049 143 vs 232 P 086 Arterial compliance and lipid profiles improved as did some QoL indices for cilostazol at 6 and 24 weeks Results Among 100 participants from the original study 88 were included in this extension study Cilostazol treatment reduced the incidence of cardiovascular events in the patients with T2DM when compared with aspirin for a 52year median followup hazard ratio 024 95 CI 007083 This minireview highlights the emerging evidence suggesting benefits of using cilostazol in treating microvascular complications associated with diabetes mellitus Methods A review of literature was conducted using PubMed and Embase databases focusing on cilostazol use in diabetes mellitus Results Cilostazol demonstrated renoprotective Cilostazol treatment for preventing adverse cardiovascular events in Diabetes mellitus type II DMII may be frequently associated with peripheral vascular disease PVD which tends to be multisegmental and often with the involvement of the crural arteries 1 The prevalence of PVD in diabetic subjects is about 10 whereas it is 26 in nondiabetic patients About 353 of patients with diabetic foot This prospective 2arm multicenter openlabel phase 4 trial reveals that in patients with type 2 diabetes mellitus who presented with symptomatic lower extremity arterial disease and had been treated with clopidogrel 75 mgd for at least 6 months the addition of cilostazol 100 mg twiceday significantly reduced the incidence of ischemic events defined as acute ischemic stroke Effect of cilostazol in treating diabetesassociated PubMed Diabetes is a major predictor of worse clinical outcomes of peripheral artery disease PAD 1 Compared with patients without diabetes the amputation cara baca hasil cek darah diabetes rate is higher in patients with diabetes because of the common involvement of the infrapopliteal arteries 2 3 In addition despite the advanced endovascular intervention era patients with diabetes have challenges in terms of improving the Effect of Cilostazol on Patients With Diabetes Who Underwent Purpose Cilostazol Pletal a phosphodiesterase3 inhibitor was approved in the United States in 1999 to reduce symptoms of intermittent claudication Cyclic adenosine monophosphate levels increase from inhibition of phosphodiesterase resulting in antiplatelet antiinflammatory and vasodilatory effects Diabetes mellitus is a chronic disease that causes endothelial and platelet Background Evidence from diabetic animal models suggests that cilostazol a cyclic AMP phosphodiesterase inhibitor used in the treatment of claudication is efficacious in the treatment of peripheral neuropathy although this is unproven in humans The main aim of this study was to assess the effects of cilostazol on neuropathic symptomatology in diabetic patients with peripheral arterial Cilostazol prevents foot ulcers in diabetic patients with peripheral The Role of Cilostazol a Phosphodiesterase3 Inhibitor in the Effect of cilostazol in treating diabetesassociated microvascular Effect of Cilostazol on Patients With Diabetes Who Underwent The Effects of Cilostazol on Peripheral Neuropathy in Diabetic Patients Type 2 diabetes mellitus T2DM is closely linked to an increased risk of CAD and cerebrovascular disease Patients with T2DM have a 24fold higher CVD risk compared to that of the general population regardless of the presenceabsence of other risk factors Thus diabetes mellitus is regarded as being equivalent to the risk of CAD The Vascular and Biochemical Effects of Cilostazol in Diabetic Patients Lee CY Wu TC Lin SJ Longterm cilostazol treatment and predictive factors on outcomes of endovascular intervention in patients with diabetes mellitus and critical limb chemotherapy and diabetes ischemia Diabetes Ther 20201117571773
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