coronary artery disease diabetes mellitus immunology - Metainflammation in Diabetic Coronary Artery Disease ada diabetes standards of care 2022 Emerging Role of Immune regulators of inflammation in obesityassociated type 2 diabetes Globally noncommunicable chronic diseases such as Type2 Diabetes Mellitus T2DM and Coronary Artery Disease CAD are posing a major threat to the world T2DM is known to potentiate CAD which had led to the coining of a new clinical entity named diabetic CAD DMCAD leading to excessive morbidi The impact of diabetes on the relationship of coronary artery disease NETosis in LongTerm Type 1 Diabetes Mellitus and Its Link to Coronary Platelet Mediated Inflammation in Coronary Artery Disease with Type 2 1 Introduction In recent years noncommunicable chronic diseases such as Type2 Diabetes Mellitus T2DM and Coronary Artery Disease CAD are posing a major threat to the world irrespective of geographical and ethnic boundaries T2DM is known to potentiate CAD which had led to the coining of a new clinical entity named diabetic CAD DMCAD leading to excessive morbidity and mortality SingleCell Immune Profiling in Coronary Artery Disease The Role of Coronary artery disease CAD is a major determinant of the longterm prognosis among patients with diabetes mellitus DM DM is associated with a 2 to 4fold increased mortality risk from heart disease Revascularization for coronary artery disease in diabetes mellitus angioplasty stents and coronary artery bypass grafting Reviews in Insulin resistance and coronary inflammation in patients with coronary To improve this situation we need to better understand the causes and mechanisms that promote CAD The foundation of our current understanding of cardiovascular risk profiling dates back to the 1950s when Framingham and other epidemiology studies associated cigarette smoking diabetes mellitus hypertension and hyperlipidemia with cardiac mortality 4 While these data were invaluable and Coronary artery disease and diabetes mellitus PMC PubMed Central PMC Sex Differences in Coronary Artery Disease makanan yg di larang untuk penderita diabetes and Diabetes Revealed by The multivessel CAD was defined as two or more main epicardial coronary artery stenoses 50 According to the American Diabetes Association criteria diabetes mellitus DM is characterized as FPG 70 mmolL 2h plasma glucose level 111 mmolL according to the oral glucose tolerance test or HbA1c 65 PreDM was diagnosed Purpose of review To summarize current work identifying inflammatory components that underlie associations between obesityassociated type 2 diabetes and coronary artery disease Recent findings Recent studies implicate immune cells as drivers of pathogenic inflammation in human type 2 diabetes Inflammatory lymphocytes characterize unhealthy adipose tissue but regional adipose volume Type 2 diabetes mellitus T2DM is a wellestablished risk factor for the development of atherosclerotic coronary artery disease Platelet hyperactivity and inflammation are associated with the development of coronary artery disease CAD in T2DM patients Background Patients with prediabetes or diabetes are at increased risk of developing cardiovascular disease and adverse outcomes Firstline coronary computed tomography angiography CTA followed by selective use of positron emission tomography PET myocardial perfusion imaging is a feasible strategy to diagnose and riskstratify patients with suspected coronary artery disease CAD The aim Metainflammation in Diabetic Coronary Artery Disease Emerging PubMed Despite the decadesold knowledge that males and people with diabetes mellitus DM are at increased risk for coronary artery disease CAD the reasons for this association are only partially understood Among the immune cells involved recent evidence supports a critical role of T cells as drivers and modifiers of CAD Keywords neutrophil extracellular traps glucose neutrophils NETs coronary artery disease type 1 diabetes mellitus Citation Aukrust SG Holte KB Opstad TB Seljeflot I Berg TJ and Helseth R 2022 NETosis in LongTerm Type 1 Diabetes Mellitus and Its Link to Coronary Artery Disease Front alat diagnosa diabetes ub Immunol 12799539 doi 103389fimmu2021799539
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