decompensated diabetes mellitus - Diabetic ketoacidosis DKA is an acute gene therapy for diabetes type 1 metabolic complication of diabetes characterized by hyperglycemia hyperketonemia and metabolic acidosis Hyperglycemia causes an osmotic diuresis with significant fluid and electrolyte loss DKA occurs mostly in type 1 diabetes mellitus It causes nausea vomiting and abdominal pain and can progress to Diabetic ketoacidosis is manifested by elevated blood glucose levels ketosis and metabolic acidosis with increased anion gap A transitory hyperchloremic acidosis with normal anion gap can appear We report a 21 years old female with a type 2 diabetes mellitus admitted to the emergency room of a Temporal Trends in the Prevalence of Diabetes Decompensation Diabetic DKA and HHS represent two extremes in the spectrum of decompensated diabetes mellitus Their pathogenesis is related to absolute or relative deficiency in insulin levels and elevations in insulin counterregulatory hormones that lead to altered metabolism of carbohydrate protein and fat and varying degrees of osmotic diuresis and dehydration ketosis and acidosis Background Disproportionate change in the burden of diabetes mellitus across various subgroups has been reported in the United States However changing landscape of the prevalence and mortality of decompensated diabetes diabetic ketoacidosis DKA and hyperosmolar hyperglycemic state HHS remains indistinct across various age gender and racial groups of hospitalized diabetics The two most common lifethreatening complications of diabetes mellitus include diabetic ketoacidosis DKA and hyperglycemic hyperosmolar syndrome HHS the patient or caregiver is unaware of the signs and symptoms of decompensated diabetes or the patient is unable to treat the progressive dehydration Certain medications that cause DKA Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome HHS are life threatening complications that occur in patients with diabetes In addition to timely identification of the precipitating cause the first step in acute diabetes hitte management of these disorders includes aggressive administration of intravenous fluids with appropriate replacement of electrolytes primarily potassium In patients Diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome review Diabetic ketoacidosis DKA and hyperglycemic hyperosmolar state HHS represent two extremes in the spectrum of marked decompensation of diabetes mellitus1261 DKA and HHS are primary reasons for admission to the hospital for patients with diabetes and are counted among the metabolic emergencies that may require management in the ICU settingDecompensated diabetes is not uncommon in patients Hyperglycemic Crises Diabetic Ketoacidosis and Hyperglycemic Management of decompensated diabetes Diabetic ketoacidosis and Management of Decompensated Diabetes ScienceDirect Management of Decompensated Diabetes Critical Care Clinics Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome Diabetic ketoacidosis DKA and hyperglycemic hyperosmolar state HHS are acute metabolic complications of diabetes mellitus that can occur in patients with both type 1 and 2 diabetes mellitus Timely diagnosis comprehensive clinical and biochemical evaluation and effective management is key to the successful resolution of DKA and HHS Critical components of the hyperglycemic crises Diabetic Ketoacidosis Diabetic ketoacidosis represents an extreme in the spectrum of de compensated diabetes mellitus that is characterized by marked catabolic disturbances in the metabolism of carbohydrate protein and fat The hallmark features of DKA are the triad of hyperglycemia acidosis and ketosis Diabetic Ketoacidosis DKA Diabetic Ketoacidosis DKA Merck Decompensated diabetes mellitus and hyperchloremic metabolic acidosis MANAGEMENT DECOMPENSATED DIABETES Critical Care Clinics DKA and HHS represent two extremes in the spectrum of decompensated diabetes mellitus Their pathogenesis is related to absolute or relative deficiency in insulin levels and elevations in insulin counterregulatory hormones that lead to altered metabolism of carbohydrate protein and fat and varying degrees of osmotic diuresis and gymnema yunnanense diabetes dehydration ketosis and acidosis
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