diabetes and atherosclerosis - Diabetes is one of the critical egregious eleven diabetes independent risk factors for the progression of cardiovascular disease and the underlying mechanism regarding this association remains poorly understood Hence it is urgent to decipher the fundamental pathophysiology and consequently provide new insights into the identification of innovative therapeutic targets for diabetic atherosclerosis It is now Atherosclerosis is accelerated in both type 1 and type 2 diabetes The hallmark of diabetes is the presence of hyperglycemia In this article we review the role of glucose in the pathogenesis of atherosclerosis Evidence obtained from epidemiological in vitro and animal studies will be reviewed in an attempt to understand the complex relationship between hyperglycemia and cardiovascular This review summarizes pathogenic mechanisms leading to the development of atherosclerosis in diabetes Contributing factors to endothelial dysfunction including nitric oxide prostaglandins oxidative stress and proinflammatory mediators as well as hemodynamic flow changes are described Diabetes and Atherosclerosis SpringerLink The link between diabetes and atherosclerosis Lucia La Sala Clinical relationships between diabetes and atherosclerosis are well established The majority of the clinical and experimental data regarding the onset of diabetes complications are associated with atherosclerosis suggesting that the impact of chronic hyperglycaemia might induce damage on vascular homeostasis mainly attributable to the endothelium function Diabetes and atherosclerosis is there a role for hyperglycemia Atherosclerotic cardiovascular disease ASCVD is accelerated in people with diabetes Dyslipidemia hyperglycemia oxidative stress and inflammation play a role via a variety of mechanisms operative in the artery wall In addition some unique features predispose people with type 1 diabetes to accelerated atherosclerosis Various organizations have created guidelines that provide advice Diabetes Mellitus Promotes the Development of Atherosclerosis The Role Cardiovascular disease remains the principal dokter spesialis penyakit dalam endokrin-metabolik-diabetes di babakan madang cause of death and disability among patients with diabetes mellitus Diabetes mellitus exacerbates mechanisms underlying atherosclerosis and heart failure Unfortunately these mechanisms are not adequately modulated by therapeutic strategies focusing solely on optimal glycemic control with currently available drugs or approaches In the setting of Clinical Update Cardiovascular Disease in Diabetes Mellitus Atherosclerosis is the cause of a majority of cardiovascular events and atherosclerosis is accelerated by diabetes and the metabolic syndrome Many risk factors are associated with the metabolic syndrome and help explain the increased cardiovascular disease CVD in that condition 1 Diabetes Mellitus and Cardiovascular Disease Arteriosclerosis Lipidlowering in diabetes An update Atherosclerosis Cardiovascular disease CVD remains a leading cause of morbidity and mortality in type 1 diabetes mellitus and type 2 diabetes mellitus T2D 13 Beyond the inherent increase in mortality in diabetic subjects when diabetes mellitus is combined with manifestations of CVD such as myocardial infarction or stroke the mortality rate is nearly doubled leading to an estimated reduction in Diabetes and atherosclerosis is there a role for hyperglycemia The Diabetes MellitusAtherosclerosis Connection The Role of Lipid and Keywords atherosclerosis diabetes mellitus NLRP3 endothelial dysfunction hyperglycemia dyslipidemia NLRP3 inhibitor Introduction Diabetes mellitus is a major and growing problem worldwide not only in the socalled developed countries 1 2 According to a recent report from the International Diabetes Federation about 537 million Diabetes Mellitus to Accelerated Atherosclerosis Shared Cellular and Keywords atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation lipid metabolism hyperglycemia 1 Introduction Atherosclerosis is a widespread chronic inflammatory disorder of the arterial wall that often leads to disability and even death At its final stages atherosclerosis manifests itself as apakah riwayat diabetes mellitus mempengaruhi kehamilan a lesion of the
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