diabetes melitus penduduk wakita pima indian - Changing Patterns of Type 2 Diabetes Incidence Among Pima Indians

diabetes melitus penduduk wakita pima indian - Dissecting the Etiology of Type 2 diabetes melitus intherintance Diabetes in the Pima Indian We examined secular trends in the incidence rate of type 2 diabetes over the past 40 years in Pima Indians a population with a very high prevalence and incidence of diabetes Previous observations 910 suggest that diabetes was either rare or largely unrecognized among Pimas around the 1900sAt that time increasing settlement of the area by people of European derivation led to diversion In this issue of Diabetes Baier et al report on the results of a targeted sequencing project focusing on the genes encoding the two subunits of the βcell K ATP channel Variants identified by wholegenome sequencing in ABCC8 and KCNJ11 in 335 Pima Indians are genotyped in 7710 individuals of full Pima Indian heritage or mixed American Indian heritage 48th Pima Indian Medically diabetes is known as diabetes mellitus which is a metabolism Address correspondence to this author at the Department of Statistics University of Burdwan Burdwan West Bengal India Tel 919232638970 Fax 9103422530452 Email rabinbwngmailcom 1876524614 Objective To review the research findings on the determinants of diabetes mellitus in Pima Indians Research Design and Methods Pima Indians in Arizona have participated in a longitudinal diabetes study that has provided data on and hypotheses about the development of NIDDM Findings from this study are reviewed and updated Risk of incident diabetes among 2024yearold Pima men and women was six times relative risk RR 95 CI 604 330 to 120 and seven times RR 95 CI 764 373 to 182 higher as compared with SA men and women respectively In those with BMI 25 kgm 2 however the risk of diabetes was over five times in SA men than in Pima Indian men The extraordinary prevalence of diabetes mellitus among the Pima Indians provides a unique opportunity to determine the factors that lead to the appearance of glucose intolerance and its sequelae If the appropriate characteristics of a sufficient number of subjects can be obat herbal pankreas diabetes followed as they change from normal to diabetic it seems likely that the Incidence of diabetes in South Asian young adults compared to Pima Indians Changing Course of Diabetic Nephropathy in the Pima Indians Changing patterns of type 2 diabetes incidence among Pima Indians Determinants of Diabetes Mellitus in the Pima Indian Mothers and Indian Epidemiologic Studies of Diabetes in the Pima Indians Determinants of Diabetes Mellitus in the Pima Indians Changing Patterns of Type 2 Diabetes Incidence Between 1965 and 2003 the average BMI in nondiabetic Pima Indians increased by 12 percent in the men and 19 percent in the women An increase in obesity was found in all age groups including children Figure 1 Given the powerful effect of obesity on the development of type 2 diabetes 13 Diabetes mellitus in the pima indians Incidence risk factors and DiabetesMetabolism Reviews is an endocrinology and metabolism journal for clinical and basic research in diabetes endocrinology metabolism obesity Skip to Article Content Skip to Article Information Search within Search term Advanced Diabetes mellitus in the pima indians Incidence risk factors and pathogenesis Obesity in the Pima Indians its magnitude and relationship with diabetes We examined trends in the incidence rate of type 2 diabetes among Pima Indians between 1965 and 2003 Research design and methods Incidence rates were computed independently in three 13year time periods in Pima Indians aged or 5 years Diabetes was defined by the presence of at least one of two criteria 1 2h plasma glucose Members of the Pima Indian population are obese on average as estimated by the body mass index BMI Young adults have had the highest BMIs and there have been modest increases in age and sexspecific mean BMIs for the past 25 y These observations suggest that the older adults have had less exposure to factors leading to obesity than have the younger adults Compared with children studied Changing Patterns of Type 2 Diabetes cara mengatasi beseran Incidence Among Pima Indians

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