diabetes mellitus eye apoptosis - Keywords cellderived microparticles vitrectomy vitreous diabetes how to test diabetes mellitus apoptosis INTRODUCTION The vitreous body fills the posterior segment of the eye and is composed primarily of collagen and hyaluronic acid A chart review was performed to acquire historical data such as presence and absence of diabetes mellitus and the reason The downregulation of AKT in diabetes leads to cell damages in various cell types such as cell apoptosis oxidative stress and cell cycle impairment in RPCs cell apoptosis in RCVECs and retinal Diabetes mellitus is associated with extensive morbidity and mortality in any human community The consequential reduction in epithelial cell proliferation and increased apoptosis impacts on epithelial wound healing Pons A Cervino A Optical quality of the diabetic eye a review Eye London England 2014 28 12711280 PMC free The Role of Immune Cells and Signaling Pathways in Diabetic Eye MDPI Diabetic Retinopathy Pathophysiology and Treatments PMC Presence and Risk Factors for Glaucoma in Patients with Diabetes Ocular complications of diabetes mellitus PMC Purpose Studies have suggested that photoreceptors PR are altered by diabetes contributing to diabetic retinopathy DR pathology Here we explored the effect of diabetes on retinal ischemic injury Methods Retinal ischemiareperfusion IR injury was caused by elevation of intraocular pressure in 10weekold BKS dbdb type 2 diabetes mellitus T2DM mice or C57BL6J mice at 4 or 12 Diabetic eye disease DED encompasses a range of ocular complications arising from diabetes mellitus including diabetic retinopathy diabetic macular edema diabetic keratopathy diabetic cataract and glaucoma These conditions are leading causes of visual impairments and blindness especially among workingage adults Despite advancements in our understanding of DED its underlying A systematic review on the impact of diabetes mellitus on the ocular RGC apoptosis and retinal nerve fiber tuak aren obat diabetes layer RNFL thinning are characteristic structural findings seen in glaucoma that have also been described in diabetic retinopathy For newly diagnosed patients with type 1 diabetes mellitus an initial eye examination is recommended within five years after diagnosis For type 2 diabetes mellitus eye Diabetes Renders Photoreceptors Susceptible to Retinal Ischemia Research progress on the pathogenesis of diabetic retinopathy Diabetic retinopathy DR is one of the common complications of type 2 diabetes mellitus T2DM and is an irreversible and blinding eye disease Based on the characteristics of the physiological anatomy of the eye the technical methods of vitreous cavity drug delivery and fundus examination for continuous assessment of efficacy are DM may increase susceptibility of retinal ganglion cells to apoptosis when there is a comorbidity with elevated IOP in glaucoma DM disrupts vascular Seifart U Strempel I The dry eye and diabetes mellitus Ophthalmologe 199491235239 Google Scholar 189 Kaiserman I Kaiserman N Nakar S Vinker S Dry eye in diabetic patients Increased apoptosis of neural retinal cells in experimental diabetes in rats and diabetes mellitus in humans was recently documented At particular risk are retinal ganglion cells which demonstrated a 10 decrease in cell number in diabetic rats compared with control eyes Apoptotic cells did not colocalize with endothelial cells Diabetic retinopathy DR is the most common complication of diabetes mellitus DM Pak J Ju ST Rook SL Esser P Mitsiades CS et al Suppression of FasFasLinduced endothelial cell apoptosis prevents diabetic bloodretinal barrier breakdown in a model of streptozotocininduced diabetes Kitsos G Kalogeropoulos C Effect Expression of Apoptosis Markers in the Retinas of Human Subjects with Vitreous microparticles contain apoptotic signals suggesting a diabetic Mechanistic insights into the alterations and diet diabetes melitus mengurangi risiko komplikasi pdf regulation of the AKT
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