diabetes mellitus hypertension chf - Heart failure HF is an underappreciated diabetes mellitus diabetes care complication of diabetes HF occurs in individuals with diabetes at higher rates even in the absence of other HF risk factors such as coronary artery disease and hypertension Comorbid ischemic heart disease and cardiovascular risk factors significantly contribute to the etiology of cardiomyopathy and HF in patients with diabetes In addition long Diabetes hypertension and cardiovascular disease development Multiple epidemiologic studies have demonstrated that diabetes mellitus amplifies the risk for the development of heart failure HF 13 The mechanisms contributing to the greater rates of HF in individuals with diabetes are likely multifactorial and include the shared and accelerated comorbid conditions of hypertension coronary artery disease obesity renal insufficiency and aortic Heart Failure in Type 2 Diabetes Mellitus Circulation Research The coexistence of diabetes mellitus DM and heart failure HF is frequent and is associated with a higher risk of hospitalization for HF and allcause and cardiovascular mortality 002 per year of HF and predominant diastolic HF in patients with type 1 DM specifically those with concurrent hypertension or coronary artery disease Diabetes Mellitus and HF AHAASA Journals Keywords Diabetes mellitus Hypertension Coronary artery disease Stroke Heart failure Background The 2019 Global Burden of Disease Study indicated that ischemic heart disease stroke and hypertensive heart disease ranked as the first second and twentysecond leading causes of death respectively in persons aged 5074 years Type 2 diabetes mellitus and heart failure HF commonly coexist with diabetes mellitus occurring in 25 of patients with chronic HF and 40 in those hospitalized with acute HF 1 Importantly the presence of diabetes mellitus in HF is associated with reduced survival and increased rates of hospitalization compared with HF patients without diabetes mellitus 1 Despite the common and The cardiovascular disease continuum begins with diabetes mellitus DM hypertension and dyslipidemia among others then results define diabetes mellitus in advanced heart failure HF and cardiovascular death The incidence of congestive heart failure in type 2 diabetes an update Diabetes Care 200427187984 doi 102337diacare2781879 Diabetes Cardiomyopathy and Heart Failure Endotext NCBI Bookshelf Patients with diabetes mellitus have gt2 the risk for developing heart failure HF HF with reduced ejection fraction and HF with preserved ejection fraction Cardiovascular outcomes hospitalization and prognosis are worse for patients with diabetes mellitus relative to those without Beyond the structural and functional changes that characterize diabetic cardiomyopathy a complex Diabetes Mellitus and Heart Failure PMC National Center for The comorbidities of hypertension diabetes mellitus obesity hyperlipidemia and metabolic syndrome are common in patients with heart failure HF and affect clinical outcomes 1 3 Interestingly although these comorbidities are associated with the development of incident HF in the general population in patients with established HF their contributory roles to clinical outcomes are not Type 2 Diabetes Mellitus and Heart Failure Cardiovascular disease and diabetes are among the most common morbidities in the US They share many common risk factors and management of one depends on the presenceabsence of the other The prevalence of CVD meaning hypertension coronary heart disease heart failure and stroke is 49 overall in US adults age 20 years or older and 40 of these are isolated hypertension1 Epidemiology Pathophysiology Diagnosis and Treatment of Heart Failure Management of Cardiovascular and Diabetes Risks Based on National Congestive Heart Failure and Diabetes Balancing Glycemic Control with Metformin and SGLT2 sodium glucose cotransporter type 2 inhibitors are preferable to use of sulfonylurea drugs in patients at high risk for HF and those with established HF Insulin is sometimes required to achieve adequate glycemic control in individuals with DM and HF Insulin use is associated with weight gain and risk of hypoglycemia Heart Failure Diabetes Mellitus dental problems with diabetes and Chronic Kidney Disease
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