diabetes mellitus metformin pdf - PDF How to Use the American grÜner tee diabetes typ 2 Diabetes Associations Type 2 Diabetes Algorithm PDF Pharmacologic Management of Type 2 Diabetes Mellitus Available Therapies Recommendations for Practical Use of Metformin a Central PDF Molecular mechanisms of action of metformin latest advances and PDF Role of metformin in the management of type 2 diabetes recent with metformin in clinical outcomes related to diabetes with less hypoglycemia and weight gain than with insulin or sulfonylureas Foundational therapy is metformin and comprehensive lifestyle management including weight management and physical activity British Medical Journal 2000 321 405412 14 14 14 production MET metformin QR quick release SGLT2i sodium glucose cotransporter 2 inhibitor T2DM type 2 diabetes mellitus TZD thia 14 14 14 14 14 zolidinedione Adapted from DeFronzo RA Eldor R AbdulGhani M Pathophysiologic approach to therapy in patients with newly diagnosed type 2 diabetes Diabetes Forecast DRUG CLASS HOW IT PRIMARILY WORKS GENERIC NAME BRAND NAME COST TYPE 2 ORAL MEDICATIONS Biguanides generic available Lowers the amount of glucose produced by the liver Metformin Glucophage Low Metformin extended release Glucophage XR Glumetza Fortamet Sulfonylureas generic available Helps beta cells in the pancreas release Metformin one of the oldest oral antidiabetic agents and still recommended by almost all current guidelines as the firstline treatment for type 2 diabetes mellitus T2DM has become the PDF Mechanism of Action Food and Drug Administration Drug Metformin Sponsor Lipha Pharmaceuticals Document NDA Submission Date Sep 29 1993 Document Date Sep 29 1993 Referral Date Oct 7 1993 Review Dates Oct 7 1993 Apr 18 1994 1 INTRODUCTION NIDDM noninsulin dependent diabetes mellitus berdasarkan hasil uji makanan tersebut bahan makanan yang harus dihindari oleh penderita diabetes accounts for 9095 of the total number of patients with diabetes mellitus 1 It is certainly Metformin 11dimethylbiguanide structure in Fig 1 improves glucose tolerance in patients with type 2 diabetes mellitus diabetes thereafter for simplicity lowering both basal and postprandial plasma glucose It decreases hepatic glucose production and intestinal absorption of glucose and type 2 diabetes mellitus who were newly diagnosed or treated with diet and exercise or who were receiving monotherapy with metformin sulfonylureas alphaglucosidase inhibitors hiazolidinediones or meglinitides or treated with combination therapy consisting of metforminglyburide at doses up to of type 2 diabetes mellitus 9 Phenformin was the rst biguanide to be marketed in the 1950s while buformin and metformin soon followed 911 This Additional indications for the use of metformin have been proposed It is an option in prediabetes to prevent progression to type 2 diabetes especially in patients with a BMI 35 kgm 2 those 60 years of age and women with a history of gestational diabetes mellitus GDM In the Diabetes Prevention Program DPP and its followup Diabetes PDF Metformin A review of its use in the treatment type 2 diabetes PDF Management of Type 2 Diabetes Mellitus Quick Reference Guide for Healthcare Professionals he Management of Type 2 Diabetes Mellitus 6th editionKEY MESSAGESRiskbased screening for pre andor T2DM in adults should be performed in individuals 30 years of age and 63 IFCC 45 mmolmol performed by an NGSPcertif tic individuals 2 abnormal values eg plasma glucose and H PDF Medical Officer Safety Review of an Original NDA Submission PDF foto diabetes bisa sembuh oleh eddy wiratama soema MEDICATIONS American Diabetes Association
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