dka vs hhs type 1 or 2 diabetes - Diabetic ketoacidosis DKA and hyperosmolar hyperglycemic epidemiology of diabetes and ramadan epidiar 2004 state HHS also known as hyperosmotic hyperglycemic nonketotic state HHNK are two of the most serious acute complications of diabetes DKA is characterized by ketoacidosis and hyperglycemia while HHS usually has more severe hyperglycemia but no ketoacidosis table 1 DKA typically affects people living with type 1 diabetes whereas HHS usually occurs in people living with type 2 diabetes HHS tends to be more dangerous than DKA but both conditions can be Hyperosmolar hyperglycemic syndrome HHS is a clinical condition that arises from a complication of diabetes mellitus This problem is most commonly seen in type 2 diabetes Won Frerichs and Dreschfeld first described the disorder around 1880 They described patients with diabetes mellitus with profound hyperglycemia and glycosuria without the classic Kussmaul breathing or acetone in the Metabolic Derangements in Diabetes HHS and DKA Diabetic ketoacidosis DKA and the hyperglycemic hyperosmolar state HHS are the two most serious acute and lifethreatening hyperglycemic emergencies in individuals with type 1 diabetes T1D and type 2 diabetes T2D Global reports clearly show an increase in the number of DKA and HHS admissions during the past decade with recent data reporting a 55 increase in the rate of DKA Diabetic ketoacidosis DKA and hyperglycemic hyperosmolar state HHS are acute metabolic complications of diabetes mellitus that can occur in patients with both type 1 and 2 diabetes mellitus Timely diagnosis comprehensive clinical and biochemical evaluation and effective management is key to the successful resolution of DKA and HHS Critical components of the hyperglycemic crises Diabetic ketoacidosis DKA is a complication of type 1 diabetes and less commonly type 2 diabetes When your blood sugar is very high ketones acidic albumin rendah pada diabetes substances can accumulate in your blood Diabetic ketoacidosis and hyperosmolar hyperglycemic state UpToDate Most patients with DKA have type 1 diabetes however patients with type 2 diabetes are also at risk during the catabolic stress of acute illness2 Contrary to popular belief DKA is more common in adults than in children1 In communitybased studies more than 40 of AfricanAmerican patients with DKA were 40 years of age and more than 20 were 55 years of age3 Many of these adult patients HHS is the type 2 diabetes equivalent of diabetic ketoacidosis DKA in type 1 diabetes individuals Its metabolic differences occur because in individuals with type 2 diabetes mellitus there is a small quantity of insulin remaining enough to suppress lipolysis and the associated acidosis Hyperosmolar Hyperglycemic Syndrome StatPearls NCBI Bookshelf Hyperglycemic Crises Diabetic Ketoacidosis and Hyperglycemic DKA HHS People affected Most commonly affects people with Type 1 diabetes Most commonly affects people with Type 2 diabetes Time to develop Develops quickly often within 24 hours Develops more slowly usually within days to weeks Blood sugar level Usually above 250 mgdL Higher than 600 mgdL Urine or blood ketones Present DKA and HHS compare onset diagnosis and treatment DKA typically occurs in patients with Type 1 diabetes although prevalence in those with Type 2 diabetes is rising accounting for an estimated 1 in 5 cases To diagnose DKA these three elements must be present diabetes hyperglycemia ketones serum and aniongap acidosis HHNS vs DKA Symptoms Causes and Treatments Healthline Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome Hyperglycemic Crises in Adults With Diabetes A Consensus Report Hyperosmolar Hyperglycemic State HHS Cleveland Clinic DKA vs HHS Differences similarities and how many carbs per day with gestational diabetes more Medical News Today
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