effect of diabetes militis risk on latent tb infections - Background Previous studies have demonstrated an monogenic diabetes adalah association between diabetes mellitus DM and latent tuberculosis infection LTBI This study was conducted to update the current understanding of the association between DM and LTBI By conducting a systematic review and metaanalysis using adjusted odds ratios aOR or risk ratios aRR we aimed to further explore the association between DM Effect of diabetes mellitus on risk of latent TB infection in a high TB Background The cooccurrence of diabetes mellitus DM and tuberculosis TB cannot be overemphasised because of the high prevalence of each disease throughout the world 1 Previous studies found that DM affects TB disease presentation leads to poor treatment outcomes and increases the risk for active TB 1 2 The recently published WHO guideline recommends screening for active TB with DM 3 Abbreviations DM diabetes mellitus IGRA interferonγ release assay LTBI latent tuberculosis infection TST tuberculin skin test aOR adjusted odds ratios aRR adjusted risk ratios NS Not specified a Highrisk people with active TB contact health care workers and patients with malignancy endstage renal disease liver cirrhosis postorgan transplantation autoimmune diseases and Diabetes Mellitus and Latent Tuberculosis Infection A Systemic Review Diabetes mellitus and tuberculosis a systematic review and meta Articles were excluded if met any following criteria 1 irrelevant to the subject of the metaanalysis 2 studies with insufficient data to calculate the odds ratio or assess the pooled effect of diabetes mellitus on risk of latent tuberculosis infection 3 duplicated or overlapped articles 4 studies in lack of the definition of DM or Abstract Diabetes is a major risk factor for tuberculosis TB Diabetes increases the risk of the progression from latent tuberculosis infection LTBI to active pulmonary TB and TB patients with diabetes are at greater risk of more severe disease and adverse TB treatment outcomes compared to TB patients without comorbidities Impact of diabetes mellitus on immunity to latent tuberculosis Background The estimated global latent diabetes gastroparesis adalah tuberculosis infection LTBI burden indicates a large reservoir of population at risk of developing active tuberculosis TB Previous studies suggested diabetes mellitus DM might associate with LTBI though still controversial We aimed to systematically assess the association between DM and LTBI The Association Between Diabetes Mellitus and the Risk of Latent Tuberculosis TB is an infectious disease that poses a major health threat and is one of the leading causes of death worldwide Following exposure to Mycobacterium tuberculosis Mtb bacilli hosts who fail to clear Mtb end up in a state of latent tuberculosis infection LTBI in which the bacteria are contained but not eliminated Type 2 diabetes mellitus DM is a noncommunicable disease Tuberculosis remains a major infectious disease globally it caused 15 millions deaths in 2014 1 2Following initial contact with viable bacilli hosts who fail to clear all Mycobacterium tuberculosis can progress to the status of latent tuberculosis infection LTBI and have a lifetime risk of 515 to further progress into active tuberculosis DiabetesAssociated Susceptibility to Tuberculosis Contribution of The Association Between Diabetes Mellitus and the Risk of Latent Diabetes mellitus and latent tuberculosis infection an updated meta Diabetes mellitus and latent tuberculosis infection an updated meta Introduction Metaanalyses conducted so far on the association between diabetes mellitus DM and the tuberculosis TB development risk did not sufficiently take confounders into account in their estimates The objective of this systematic review was to determine whether DM is associated with an increased risk of developing TB with a sensitivity analyses incorporating a wider range of Impact of diabetes mellitus on tuberculosis prevention diagnosis and Abstract The coexistence of diabetes mellitus DM and tuberculosis TB presents a significant global burden with DM being recognized as a major risk factor for TB the review emphasizes the need for further research on the mechanisms underlying DM reactivation in latent TB infection LTBI In summary there diabetes treatment in india is a close relationship
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