efficasy beta lactam compare quinolon for uti in patients diabetes - PDF Oral quinolones versus intravenous βlactam how to control diabetes immediately for the treatment of acute Clinical effectiveness of betalactams versus fluoroquinolones as Outcomes of highdose oral betalactam definitive therapy compared to The new betalactamasestable cephalosporins Ann Intern Med 97 1982 Efficacy of imipenemcilastatin in patients with severe bacterial infections J Antimicrob Chemother 18 Suppl E 1986 Use of quinolones in urinary tract infections and prostatitis Rev Infect Dis 11 Suppl 5 1989 pp 13211337 Google Scholar ResultsSignificantly more patients with than without diabetes were 65 years of age or older patients with diabetes were also more likely to weigh 75 kg at baseline 571 vs 445 to have Oral βlactam antibiotics alone without preceding parenteral antibiotics have been shown to be associated with higher clinical recurrence rates in UTI trials with or without bacteremia 23233 In UTI trials in which βlactam antibiotics were used as stepdown therapy after initial intravenous antibiotics clinical cure rates were either Pyelonephritis and Urinary Tract Infections Associated with Bacteremia Uncomplicated Pyelonephritis Antibiotic Duration Trimethoprimsulfamethoxazole 714 days Fluoroquinolones 57 days Betalactams IV betalactam therapy4 7 days IV betalactam therapy4 followed by oral betalactam5 or oral trimethoprimsulfamethoxazole therapy 714 days Patients with type 2 diabetes aged 20 and hospitalized for UTIs were enrolled Patients with UTI diagnosis within one year before the admission coinfections at the admission or 2 pathogens in the urine cultures were excluded The primary outcome was empiric treatment failure Oral βLactam Antibiotics vs Fluoroquinolones or Trimethoprim Quinolones overt diabetes mellitus in the treatment of complicated urinary tract infection Clinical effectiveness of betalactams versus fluoroquinolones as PDF Guidelines for Treatment of Urinary Tract mihmsorg Efficacy and safety of quinolones vs other antimicrobials for the Clinical effectiveness of betalactams versus fluoroquinolones as Background Diabetic patients are at risk of severe urinary tract infections UTIs Due to the emerging resistance rates to fluoroquinolones and βlactams we aimed to evaluate the effectiveness of βlactams versus fluoroquinolones as empirical therapy for diabetic patients hospitalized for UTIs Methods A retrospective cohort study was conducted in a medical center in Taiwan between 2016 Treatment of recurrent urinary tract infection occurred in 16 213 patients in the betalactam group and 14 118 patients in the standard treatment group p 0073 however only 5 67 patients in the betalactam group and 6 5 patients in the standard therapy group had urinary symptoms documented at followup p 0510 Introduction and hypothesis In the present study we aimed to compare the efficacy and safety of quinolones with trimethoprimsulfamethoxazole TMPSMX nitrofurantoin fosfomycin and βlactams for the treatment of uncomplicated urinary tract infections UTIs in adults Methods All controlled clinical trials assessing quinolones for uncomplicated UTIs in adults were searched from PubMed Keywords Urinary tract infections Acute focal pyelonephritis Βlactam Quinolones Received 20 October 2023 Accepted 29 May 2024 Published online 10 June 2024 patients 41 155 had diabetes 47 178 were renal transplant recipients and 63 bolehkah penderita diabetes minum susu uht 239 were receiving immu
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