epidemiology diabetes children in the world journal - Research in context Evidence before this what does reversing diabetes mean study The Global Burden of Diseases Injuries and Risk Factors Study GBD generates publicly available estimates of total inclusive of type 1 and type 2 diabetes deaths prevalence years of life lost YLLs years lived with disability YLDs and disabilityadjusted lifeyears DALYs at the global superregion region and country and Global regional and national burden of diabetes from 1990 to 2021 Worldwide estimates of incidence of type 2 diabetes in children and Diabetes mellitus is a leading cause of mortality and reduced life expectancy We aim to estimate the burden of diabetes by type year regions and socioeconomic status in 195 countries and Recently the global epidemic of childhood obesity has led to an increasing prevalence of type 2 diabetes T2D in children 13 The main underlying factors are obesity and poor lifestyle eg sedentary living and most affected children have a parental history of T2D 36 Obesity the most prominent risk factor for T2D requires lifestyle Importance Diabetes in children is a global epidemic that causes various medical conditions associated with an increased incidence of premature death Objective To investigate the trends in diabetes incidence mortality and disabilityadjusted lifeyears DALYs in children with risk factors for diabetesassociated death from 1990 to 2019 Global Regional and National Epidemiology of Diabetes in Children Epidemiology of Type 2 Diabetes Global Burden of Disease and Global Regional and National Epidemiology of Diabetes in Children Most of our current knowledge about the epidemiology of youthonset diabetes in the US comes from the SEARCH For Diabetes in Youth study a populationbased study that surveilled physiciandiagnosed diabetes in Washington South Carolina Ohio Colorado and California plus select American Indian reservations from 2000 to 2020 Based on the most recent SEARCH data type 2 diabetes Diabetes remains a substantial side effects of diabetes tablets public health issue Type 2 diabetes which makes up the bulk of diabetes cases is largely preventable and in some cases potentially reversible if identified and managed early in the disease course However all evidence indicates that diabetes prevalence is increasing worldwide primarily due to a rise in obesity caused by multiple factors Preventing and Better epidemiological data collection systems eg diabetes registries with national population coverage and standard and reliable methods for case ascertainment and classification of diabetes type are warranted for better understanding the epidemiology of type 2 diabetes in children and adolescents Aims We aimed to conduct a systematic review of published studies on the incidence of type 2 diabetes in children and adolescents aged under 20 years and provide worldwide incidence estimates for 2021 Methods We used MEDLINE and EMBASE to identify studies reporting type 2 diabetes incidence in children and adolescents published between Jan 2000 and April 2021 Keywords Diabetes Prevalence Projections Health economics Epidemiology International Diabetes Federation 1 Introduction Diabetes has emerged as one of the most serious and common chronic diseases of our times causing life threatening disabling and costly complications and reducing life expectancy The global prevalence of diabetes IDF Diabetes Atlas Global regional and countrylevel diabetes Global regional and national burden of diabetes from 1990 to 2021 Worldwide estimates of incidence of type 2 diabetes in children and Age distribution of diabetes mellitus type 2 worldwide A Incidence vs prevalence both 2017 B Incidence in 1990 vs 2017 p 00001 chisquare test Even though it afflicts individuals later in life type 2 diabetes ranks seventh among the leading causes of disability and years of life lost DALYs YouthOnset Type 2 Diabetes The Epidemiology of an Awakening Epidemic Global regional and national burden and trend apa perbedaan kolesterol dan diabetes of diabetes in 195
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