evaluation of renal function in diabetes plus dyslipidemia - 1 Introduction Dyslipoproteinemia is highly prevalent diagnosis diabetes millitus in diabetes chronic kidney disease CKD and diabetic kidney disease 13Dyslipoproteinemia is associated with the development of CKD and renal function impairment in the general population and in diabetic patients 47When renal function declines or proteinuria increases dyslipoproteinemia becomes severe 8 9 Renal function deterioration in adult patients with type2 diabetes Diabetic Nephropathy Update on Pillars of Therapy Slowing Progression Diabetes Management in Chronic Kidney Disease A Consensus Report by Diabetic kidney disease DKD develops in up 3040 of all individuals with diabetes and is the leading cause of ESRD worldwide accounting for almost half of patients on renal replacement treatment The loss of kidney function corresponds with histopathological changes including progressive thickening of the glomerular and tubular basement membranes mesangial expansion podocyte Treatment and impact of dyslipidemia in diabetic nephropathy If renal function progresses to an eGFR 15 mLmin173 m 2 due to the risk of a cardiovascular event or the initiation of dialysis it is advisable to evaluate its interruption in an attempt to delay the start of dialysis Another drug of interest is finerenone nonsteroidal antagonist of the mineralocorticoid receptor Background To explore in a large group of patients with type2 diabetes T2DM renal function decline in terms of the slope of the estimated glomerular filtration rate eGFR over time and to find out how classical risk factors such as the presence of hypertension dyslipidemia and microalbuminuria affect the renal function Methods The analysis included 32492 adult T2DM patients from Atherogenic dyslipidemia and diabetic nephropathy Journal Springer Management of Kidney Failure in Patients with Diabetes Mellitus What Early detection of diabetic nephropathy in patient with type 2 diabetes 1 Introduction Diabetes mellitus is a critical health issue worldwide According to data from the International Diabetes Federation 371 million adults were diagnosed with diabetes and an estimated 48 million people died of the disease in 2012 The number of adults with diabetes may increase to 552 million in 2030 Type diabetes melitus pada anak pdf 2 diabetes T2D accounts for more than 90 of all cases of The microvascular complications of diabetes induce to renal damage known as diabetic nephropathy DN the most common complication of type 2 diabetes mellitus 5 and it is the leading cause of endstage renal disease worldwide which is associated with high morbidity and mortality 6 It develops in approximately 40 of patients with diabetes 7 after 10 years of type 2 diabetes mellitus were Dyslipoproteinemia and Impairment of Renal Function in Diabetic Kidney Background Diabetes is the leading risk factor for the development of renal impairment and endstage renal disease Irrespective of a potential causal relationship chronic kidney disease CKD defined as an eGFR 60 mLmin173 m 2 OR an eGFR 60 mLmin173 m 2 together with albuminuria 30 mgg affects approximately 50 of the patients with type 2 diabetes mellitus T2DM 2 3 Recent epidemiological research revealed that dyslipidemia is a risk factor for development and progression of diabetic nephropathy Results from interventional studies revealed the possibility that antihyperlipidemic agents have a better effect on diabetic nephropathy through improvement of albuminuria and loss of renal function In addition dyslipidemia may be a consequence of albuminuria Renal function deterioration in adult patients with type2 diabetes The goal of this consensus report was to identify and highlight shared recommendations from the ADA 2022 Standards of Medical Care in Diabetes hereafter called Standards of Care and KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease 12A joint writing group of ADA and KDIGO representatives convened to compare and contrast ADA and KDIGO recommendations Diabetic kidney disease DKD is a serious microvascular complication that affects approximately 40 of individuals with diabetes Presently the leading cause of endstage kidney disease ESKD worldwide DKD affects 700 million people and it disproportionately affects those who are socially disadvantaged The global percentage of prevalent ESKD patients with diabetes increased from 190 Dyslipidemia Kidney Disease and diabetes diagnosa pada dewasa Cardiovascular Disease in Diabetic
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