gender and diabetes mellitus - Gender differences in reported frequency and early onset type 1 diabetes consequences of The presence type and magnitude of sex and gender differences in type 2 diabetes mellitus and diabetesmediated risk of cardiovascular disease CVD have historically been underappreciated Epidemiological studies demonstrate clinically relevant sex and gender differences in the rates of type 2 diabetes in youth 2345678 and midlife 9101112 In medicine there is growing evidence that gender differences are important and lead to variations in the pathophysiology and treatment of many diseases with traits that appear to be particularly relevant in influencing the outcomes of many morbid forms Today the inclusion of gender in biomedical research to improve the scientific quality and scientific relevance of knowledge of Type 2 diabetes mellitus is associated with an approximate twofold increase in the risk of allcause mortality as well as death from cardiovascular disease Gernot R et al Gender disparities in diabetes and coronary heart disease medication among patients with type 2 diabetes results from the Diana study Cardiovasc Diabetol 20121188 Sex differences in type 2 diabetes PubMed Influence of Gender in Diabetes Mellitus and Its Complication MDPI Sex and Gender Differences in Risk Pathophysiology and Complications Sex differences in the burden of type 2 diabetes and cardiovascular Growing evidence suggests that sex and gender differences play a role in chronic disease management including diabetes 1 Gender and sex could indeed shape diabetes features from management strategies in various settings 2 to its consequences in terms of short and longterm complications and adverse events 3 For instance some studies suggest a higher risk of hypoglycemia The prevalence of type 2 diabetes mellitus is increasing in both sexes but men are usually diagnosed at a younger age and lower body fat mass than women HbA1c and fasting blood glucose in patient subpopulations by gender duration of diabetes and baseline HbA1c Diabetes Obes Metab 2018202409418 doi 101111dom13086 Graphical summary bagan patofisiologi diabetes melitus of sex differences in diabetes care and research Abbreviations AT adipose tissue F female FPG fasting plasma glucose GDM gestational diabetes mellitus GLP1 RA glucagonlike peptide1 receptor agonist IR insulin resistance MHRT menopausal hormone replacement therapy OGTT oral glucose tolerance test PCOS polycystic ovarian syndrome M male SGLT2i sodiumglucose Sex differences in metabolic regulation and diabetes Springer The steep rise of type 2 diabetes mellitus T2DM and associated complications go along with mounting evidence of clinically important sex and gender differences T2DM is more frequently diagnosed at lower age and body mass index in men however the most prominent risk factor which is obesity is more common in women Sex differences in type 2 diabetes PMC PubMed Central PMC Sex differences in the association between diabetes and risk of Gender and biological sex impact the pathogenesis of numerous diseases including metabolic disorders such as diabetes In most parts of the world diabetes is more prevalent in men than in women especially in middleaged populations In line with this considering almost all animal models males are more likely to develop obesity insulin resistance and hyperglycaemia than females in Sex and Gender Differences in Prevention of Type 2 Diabetes Keywords sex gender type 2 diabetes obesity prevention bariatric surgery sex hormones ethnicity Introduction The number of patients affected by type 2 diabetes mellitus T2DM is increasing worldwide In 2015 around 415 million people were affected and an expected number of nearly 650 million subjects in 2040 was estimated T2DM is Sex differences in type 2 diabetes an opportunity for personalized The prevalence of type 2 diabetes mellitus is increasing in both sexes but men are usually diagnosed at a younger age and lower body fat mass than women Worldwide an estimated 177 million more men than women have diabetes mellitus 2 Gender Institute Lapura Womens Health Resort Gars covid 19 vaccine and diabetes am Kamp Austria alexandrakautzkywiller
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