gestational diabetes genetic - The Genetic Architecture of Diabetes in susu diabetasol untuk diabetes Pregnancy Implications Gestational diabetes MedlinePlus Genetics Genetics of gestational diabetes mellitus PubMed New insights into the genetics of diabetes in pregnancy Distinct and shared genetic architectures of gestational diabetes Gestational diabetes mellitus GDM is the most common metabolic complication of pregnancy with a prevalence that has increased significantly in the last decade coming to affect 1218 of all pregnancies GDM is believed to be the result of a combination of genetic epigenetic and environmental factors The Pathophysiology of Gestational Diabetes Mellitus PMC About 25 of all pregnant women develop gestational diabetes mellitus GDM during their pregnancies and the prevalence has increased considerably during the last decade GDM is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy Gestational Diabetes The Genetic Landscape of Diabetes NCBI When the mother39s production of insulin is not enough to overcome the effect of the placental hormones gestational diabetes mellitus GDM results GDM is defined as carbohydrate intolerance of varying degrees of severity with onset or first recognition during pregnancy 1 Outside of pregnancy three distinct forms of diabetes mellitus are described autoimmune diabetes type 1 diabetes occurring on a background of insulin resistance type 2 and diabetes obat diabetes dan asam lambung as a result of other causes including genetic mutation diseases of the exocrine pancreas eg pancreatitis and drug or chemicalinduced diabetes such Genetic Studies of Gestational Diabetes and Glucose Metabolism in Our results suggest that the genetics of GDM risk falls into the following two distinct categories one part conventional T2D polygenic risk and one part predominantly influencing mechanisms Gestational diabetes is a disorder characterized by abnormally high levels of blood glucose also called blood sugar during pregnancy Affected women do not have diabetes before they are pregnant and most of these women go back to being nondiabetic soon after the baby is born In this review we summarize studies investigating genetics of gestational diabetes mellitus GDM and glucose metabolism in pregnancy We describe these studies in the context of the larger body of literature on type 2 diabetes T2D and glycemic trait genomics Here we provide an overview of the genetics of both pregestational and gestational diabetes followed by a review of monogenic diabetes and associated pregnancyspecific implications Genetics and Epigenetics New Insight on Gestational Diabetes Gestational diabetes is a complex metabolic condition thought to have a strong genetic predisposition A large genomewide association study of participants from Finland fenugreek benefits for diabetes 2 sheds light on the
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