mage diabetes - Background Glycemic variability is currently under diabetes tipo 2 alimentos permitidos scrutiny as a possible predictor of the complications of diabetes The manual process for estimating a now classical measure of glycemic variability the mean amplitude of glycemic excursion MAGE is both tedious and prone to error and there is a special need for an automated method to calculate the MAGE from continuous glucose monitoring Calculating the mean amplitude of glycemic excursion from continuous Glycemic Variability How to Measure and Its Clinical Implication for In a crosssectional study we analyzed 24h glucose levels measured using CGM iPro2 in 99 patients with type 2 diabetes To estimate numerical relation between M and SD we calculated ratio of M to SD MSD as follows sum of the 20 previous reports 20r with M SD n sum of 20r with n resulting in an MSD of approximately 24 Glycemic Variability Assessment with a 14Day Continuous Glucose Glycemic variability Measurement target impact on complications of Keywords glycemic variability continuous glucose monitoring freestyle libre MAGE type 1 diabetes Introduction During the last decade a lot of attention has focused on glycemic variability GV 12 Indeed several studies have shown an independent association between GV and diabetic complications in patients with type 1 or type 2 diabetes 620P Simple MAGE American Diabetes Association Glucose variability is increasingly regarded as a risk factor for diabetesrelated complications The mean amplitude of glycemic excursions MAGE is a common measure of glucose variability and is defined by Service et al 1 as the arithmetic mean of the heights of glucose excursions that are greater than the standard deviation of the glucose Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the MAGE was designed to capture mealtimerelated glucose excursions To separate ikan yang boleh dimakan penderita diabetes mealtimeinduced from other glucose excursions investigations were done in healthy volunteers and it was A characteristic of blood glucose behavior the mean amplitude of glycemic excursion MAGE was measured MAGE was small for normals range 22 to 60 mg100 ml larger for stable diabetics 67 to 82 mg100 ml and largest for unstable diabetics 119 to 200 mg100 ml Glycemic Variability Assessment with a 14Day Continuous Glucose Journal of Diabetes Investigation is a clinical and experimental diabetes research journal publishing basic science CV mean amplitude of glycemic excursions MAGE high blood glucose index 9 low blood glucose index 10 area under the curve for hypoglycemia and continuous overall net glycemic action CONGA 11 Table 1 MAGE Diabetesspecific metric of the amplitude of glucose excursions Mean of glycemic excursions from nadir to peak blood glucose level and vice versa that are 1 SD of blood glucose mean it takes into account glycemic peaks and nadirs occurring daily Mean Amplitude of Glycemic Excursions a Measure of Diabetic Glucose Variability Where It Is Important and How to Measure It OpenSource Algorithm to Calculate Mean Amplitude of Glycemic Effects of the Mean Amplitude of Glycemic Excursions and Vascular BackgroundMean amplitude of glycemic excursion MAGE is commonly used to gauge the degree of glucose level fluctuations MAGE plays a significant role in vascular endothelial dysfunction and cardiovascular events in patients with diabetes mellitus DM but its significance is not clear in nonDM patients Thus we examined the impact of MAGE and vascular endothelial dysfunction on clinical Mean amplitude of glucose excursion MAGE is considered as the gold standard for assessing the shortterm withinday glycemic variability GV which is an important component of overall glycemic control We evaluated in 68 patients with type 1 diabetes MAGE during three 2day periods day1day3 diabetes melitus key day6day8 day11day13 and during
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