microangiopathy and macroangiopathy in diabetes - Diabetic Microangiopathy an overview ScienceDirect Topics diabetes eten lijst Diabetic microangiopathy including retinopathy is characterized by abnormal growth and leakage of small blood vessels resulting in local edema and functional impairment of the depending tissues Mechanisms leading to the impairment of microcirculation in diabetes are multiple and still largely un Although persistent hyperglycemia contributes greatly to the progression of diabetic micro and macroangiopathy microangiopathy progresses more rapidly than macroangiopathy in some type 2 diabetic patients with the opposite being true in others This study was conducted to identify factors responsible for such dissociation Diabetes can involve the liver in several distinct ways nonalcoholic fatty liver disease glycogenic hepatopathy diabetic microangiopathy and diabetic hepatosclerosis 8491 Microangiopathy is the cause of most of the complications of diabetes including but not limited to diabetic nephropathy peripheral neuropathy and retinopathy 8791 Histologically the hepatic arterioles appear Microvasular and macrovascular complications in diabetes mellitus Introduction Type 2 diabetes mellitus T2DM is a metabolic disorder with high blood sugar levels due to the bodys resistance to insulin T2DM affects 90 of individuals with diabetes and poses a significant threat to human health making it a public health concern globally 24The complications of diabetes can be characterized on the basis of their involvement in heart and brain Diabetic vasculopathy is classified as macroangiopathy and microangiopathy Macroangiopathy includes AS of large and medium arteries aorta coronary renal basilar and peripheral arteries Microvascular and Macrovascular Complications of Diabetes The diabetes continuum Heart involvement in diabetes may not be only a macrovascular disease where there is Orchestra of contributing factors to the development of diabetic cardiomyopathy concerning fatty acid and glucose complex structural macrovascular derangements such as ayuno intermitente diabetes tipo 1 hypertrophy and loss of function due to glycation but also a microvascular involvement following common soil In addition the observed relationship between ABI and subepidermal ORT4MBM might support concurrent micro and macroangiopathy in type 2 diabetes patients which is part of generalized microangiopathy Diabetes Care 2014 37 11651168 Google Scholar 8 Lin JH Duffy JL Roginsky MS Microcirculation in diabetes mellitus a study Dissociation of Microangiopathy and Macroangiopathy in Patients With Cutaneous microangiopathy in patients with type 2 diabetes Impaired A Narrative Review of Diabetic Macroangiopathy From Molecular Diabetic retinopathy may be the most common microvascular complication of diabetes It is responsible for 10000 new cases of blindness every year in the United States alone 1 The risk of developing diabetic retinopathy or other microvascular complications of diabetes depends on both the duration and the severity of hyperglycemia Development of diabetic retinopathy in patients with type Common mechanisms underlying diabetic vascular complications focus on Diabetic vascular complications DVCs including macro and micro angiopathy account for a high percentage of mortality in patients with diabetes mellitus DM Endothelial dysfunction is the initial and role step for the pathogenesis of DVCs Hyperglycemia and lipid metabolism disorders contribute to endothelial dysfunction via direct injury of metabolism products crosstalk between Diabetic vascular diseases molecular mechanisms and therapeutic Pathogenesis of diabetic macro and microangiopathy PubMed Epidemiological investigations reveal that we must expect a rapid increase in cases of diabetes mellitus in the next few years As a result vascular complications in the form of macro and microangiopathy are also expected to arise more frequently A classical example of macroangiopathy is coronary Diabetic microangiopathy Pathogenetic diabetes guideline ramadan insights and novel PubMed
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