mikroangiopati diabetes - Diabetic microangiopathy Pathogenetic insights and novel PubMed

mikroangiopati diabetes - Microangiopathy also known as microvascular disease gejala penyakit diabetes insipidus small vessel disease SVD or microvascular dysfunction is a disease of the microvessels small blood vessels in the microcirculation 1 It can be contrasted to macroangiopathies such as atherosclerosis where large and mediumsized arteries eg aorta carotid and coronary arteries are primarily affected DIABETES A H BARNETT Birmingham SUMMARY The mechanism of development of microangiopathy is incompletely understood but relates to a number of ultrastructural biochemical and haemostatic processes Abstract Diabetic microangiopathy including retinopathy is characterized by abnormal growth and leakage of small blood vessels resulting in local edema and functional impairment of the depending tissues Mechanisms leading to the impairment of microcirculation in diabetes are multiple and still largely unclear Functional Microangiopathy in Diabetes Mellitus Diabetic microangiopathy Pathogenetic insights and novel PubMed Microangiopathy in diabetes mellitus I Causes prevention and Abstract Microangiopathy is the major cause of death in Insulin Dependent Diabetes Mellitus However the pathogenesis of microangiopathy is still far from clear This paper is a review of the literature on diabetic microangiopathy and discusses the current theories concerning its causes prevention and treatment Functional Microangiopathy in Diabetes Mellitus The present knowledge of the state of the microvasculature in diabetic subjects early during the course of the disease and prior to any clinical signs of retinopathy and nephropathy is reviewed Functional changes in the peripheral vascular bed have been demonstrated by various methods in the Metabolic complications in diabetes are primary triggered by hyperglycemia which is caused by changes in glycolysis 26 27 as well as depression of glucose uptake through glucose transporters 1 and askep diabetes tipe 2 4 GLUT1 and 4 in the muscleIn fact lower levels of mRNA and proteins for GLUT1 and 4 have been reported in the diabetic heart 2832On the other hand vascular endothelial cells the major Cutaneous microangiopathy in patients with type 2 diabetes Impaired PDF ORIGIN OF THE MICROANGIOPATHIC CHANGES IN DIABETES Nature Chronic venous disease and diabetic microangiopathy PubMed Diabetic Microangiopathy an overview ScienceDirect Topics However microvascular changes in diabetes patients are not confined to just those findings and are generalizable to a wide variety of organs including the skin4 muscle5 heart6 brain7 and gingiva8 Patients with type 2 diabetes with retinopathy and nephropathy reportedly show pronounced skin microangiopathy4 Microangiopathy Wikipedia Diabetes can involve the liver in several distinct ways nonalcoholic fatty liver disease glycogenic hepatopathy diabetic microangiopathy and diabetic hepatosclerosis 8491 Microangiopathy is the cause of most of the complications of diabetes including but not limited to diabetic nephropathy peripheral neuropathy and retinopathy 8791 Histologically the hepatic arterioles appear The etiology of chronic venous disease is multifactorial involving hemodynamic genetic and environmental factors which result in changes to the venous endothelium and structural wall as well as inflammation Inflammation endothelial dysfunction and hyperfiltration or leakage are commonly observed in diabetes mellitus and cause various Role of microangiopathy in diabetic cardiomyopathy Diabetic microangiopathy Pathogenetic insights and novel therapeutic Graphical abstract Diabetic microangiopathy including retinopathy is characterized by abnormal growth and leakage of small blood vessels resulting in local edema and functional impairment of the depending tissues Mechanisms that impair the microcirculation in diabetes are multiple and to a travel insurance diabetes over 50 large extent still unclear

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