non insulin dependent diabetes mellitus with multiple complications - Diabetes is justly recognized as an can heat affect diabetes emerging global epidemic representing one of the leading causes of morbidity and mortality worldwide Hyperglycemia the common characteristic of both type 1 diabetes mellitus T1DM and type 2 diabetes mellitus T2DM has the potential to cause serious complications due to its insidious and chronic nature Complications Type 2 diabetes affects many major organs including the heart blood vessels nerves eyes and kidneys Also factors that increase the risk of diabetes are risk factors for other serious diseases Managing diabetes and controlling blood sugar can lower the risk for these complications and other medical conditions including Type 2 diabetes can cause complications such as heart disease stroke and kidney disease To reduce risks a person can regularly check their blood glucose maintain a healthy lifestyle and Keywords Diabetes mellitus DM diabetic nephropathy DN dyslipidemia apolipoprotein M apoM obstructive sleep apnea OSA Introduction Diabetes mellitus DM as a growing epidemic of bipolar disorder affects near 56 of the worlds population Its global prevalence was about 8 in 2011 and is predicted to rise to 10 by 2030 Diabetes mellitus is taken from the Greek word diabetes meaning siphon to pass through and the Latin word mellitus meaning sweet A review of the history shows that the term diabetes was first used by Apollonius of Memphis around 250 to 300 BC Ancient Greek Indian and Egyptian civilizations discovered the sweet nature of urine in this condition and hence the propagation of the word Noninsulindependent diabetes mellitus NIDDM is a major health concern for clinicians who are responsible for the care of an aging population The relationship between hyperglycemia and the chronic complications of retinopathy nephropathy and neuropathy has been established in patients with insulindependent diabetes mellitus and it is extremely likely apa beda nya gula darah kencing manis dan diabetes that such a relationship exists in Chronic hyperglycemia is a metabolic disorder caused by either a lack of insulin secretion impaired insulin action or both Notably insulin plays an important role as an anabolic hormone affecting the metabolism of carbohydrates lipids and proteins 1The metabolic abnormalities associated with diabetes mainly affect tissues such as adipose tissue skeletal muscles and the liver due to Complications of Diabetes Mellitus Complications of Diabetes Mellitus Pharmacologic Treatment Options for NonInsulinDependent Diabetes Mellitus New insights into diabetes mellitus and its complications a narrative Complications of Diabetes PMC PubMed Central PMC Type 2 diabetes Symptoms and causes Mayo Clinic Diabetes Mellitus DM Diabetes Mellitus DM MSD MSD Manuals Non Insulin Dependent Diabetes Mellitus ScienceDirect In patients with diabetes mellitus years of poorly controlled hyperglycemia lead to multiple primarily vascular complications that affect small vessels microvascular large vessels macrovascular or both The mechanisms by which vascular disease develops include Glycosylation of serum and tissue proteins with formation of advanced glycation end products Diabetes StatPearls NCBI Bookshelf National Center for Resistance to insulin In type 2 diabetes mellitus previously called adultonset or non insulindependent insulin secretion is inadequate because patients have developed resistance to insulinHepatic insulin resistance leads to an inability to suppress hepatic glucose production and peripheral insulin resistance impairs peripheral glucose uptake This combination gives rise to fasting Type 2 diabetes With and without complications Medical News Today Diabetes mellitus Classification mediators and complications A gate Cardiovascular complications of noninsulindependent diabetes The JCRLAcp rat Tod A Clark Grant N Pierce in Journal of Pharmacological and Toxicological Methods 2000 Noninsulindependent type II diabetes mellitus NIDDM is a condition presenting not only elevated plasma glucose levels but also high circulating insulin levels high serum lipid levels and drink diabetes in most cases obesity
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