what organ malfunction in diabetes mellitus patients? - Pathophysiology of type 2 diabetes and diabetes 2 pathogenesis the impact of altered metabolic How Diabetes Can Affect Your Body Infographic CDC Complications of diabetes a disease affecting all organs The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Complications of Diabetes Mellitus Complications of Diabetes Mellitus Type 2 Diabetes StatPearls NCBI Bookshelf How Are Your Body Organs Affected by Diabetes Verywell Health Graphic text How diabetes can affect your body Having high blood sugar from diabetes over time can cause serious health complications Heart Damaging blood vessels and causing high blood pressure a heart attack or heart failure Eyes Damaging the small blood vessels at the back of the eyes leading to vision loss Feet Reducing blood flow and damaging nerves making a wound Houshang A Alizadeh M Diabetes mellitus and pancreas an overview JOP J Pancreas 20202147273 National Institute of Diabetes and Digestive and Kidney Diseases Diabetes gum disease and other related conditions National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Centers for Disease Control and Prevention Patients death is mainly due to the acute respiratory distress syndrome disseminated intravascular coagulation hemorrhage coagulopathy acute organ eg kidney heart liver injury multiorgan failure and secondary bacterial infections Editorial Molecular Pathophysiology of DiabetesRelated Organ Injury In patients with diabetes mellitus years of poorly controlled hyperglycemia lead to multiple primarily vascular complications that affect small vessels microvascular large vessels macrovascular or both The mechanisms by which vascular disease develops include Glycosylation of serum and tissue proteins with formation of advanced glycation end products Diabetes mellitus is a devastating chronic metabolic disorder characterized by dysregulated insulin secretion with which may result in persistent diabetes in patients with susceptibility to the disease liver and pancreas may lead to lipoapoptosis and organ failure Lipotoxicity in other tissues and organs provokes several diabetes militus menurut ada metabolic The kidneys can malfunction resulting in chronic kidney disease that may require dialysis or kidney transplantationDoctors usually check the urine of people with diabetes for abnormally high levels of protein albumin which is an early sign of kidney damageAt the earliest sign of kidney complications people are often given medications that slow the progression of kidney damage for Many common cancers are related to type 2 diabetes This includes breast stomach colorectal kidney and endometrial cancers In addition survival of cancer patients with preexisting diabetes is far worse than those without diabetes Skin and Nails Patients with type 2 diabetes commonly manifest some form of skin disease The prevalence of diabetes mellitus is increasing rapidly around the world This disease accompanies by a large variety of multiple organs injuries For example diabetic kidney disease DKD is affecting one in three patients with diabetes and cardiovascular CV disease is the leading cause of death for these patients The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Diabetes mellitus DM is a chronic metabolic disorder characterized by persistent hyperglycemia It may be due to impaired insulin secretion resistance to peripheral actions of insulin or both According to the International Diabetes Federation IDF approximately 415 million adults between the ages of 20 to 79 years had diabetes mellitus in 20151 DM is proving to be a global public Figure 2Blood vessels in healthy individuals and T2DM patients A normal blood flow in healthy individualsB A close view of HDL binding to its receptors on the surface of ECs that results in the activation of antiinflammatory cascadesC Blood vessels in T2DM patients During the progression of the disease red blood cells become glycated while activated ECs synthesize elevated levels Complications of Diabetes Mellitus not feeling hungry diabetes Complications of Diabetes Mellitus
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