why are patients with diabetes more susceptible to infections - Diabetes and the Risk of Infection type 1 diabetes cell A National Cohort Study Your Immune System and Diabetes Diabetes CDC 723 17351 By Diabetes Daily Staff December 13th 2023 Shutterstock Diabetes significantly increases the risk of infections If you have diabetes your body is more likely to get infected in the first place and infections will grow more quickly and require medical care more rapidly Infections in a person with diabetes can range from Diabetes and infection review of the epidemiology Springer Infections in patients with diabetes mellitus A review of pathogenesis Table 1 summarizes baseline characteristics of the study population Participants with diabetes had a meanstandard deviation age of 582133 years 504 were women and 366 had been diagnosed with diabetes more than 4 years before the inception of the cohort Of the person with diabetes 190 were using insulin People with diabetes mellitus have an increased risk of many common infections such as urinary tract infections lower respiratory tract infections and skinsoft tissue infections This is caused by a combination of systemic and local host factors and also specific organism characteristics Individuals with diabetes mellitus also tend to acquire more complex infections such as emphysematous Susceptibility for Some Infectious Diseases in Patients With Diabetes How diabetes affects your immune system High blood sugar adds stress to your body and makes nearly every system work harder This includes the white blood cells of your immune system If you have diabetes your immune system might be weakened and less effective High blood sugar can also trigger a protective immune response called inflammation Infections in people with diabetes Medicine DM both type 1 and type 2 is associated with a high risk of infection A large retrospective study of primary care patients revealed that diabetes is likely to account for diabetes care in nursing homes 6 of infectionrelated hospitalizations and 12 of infectionrelated deaths with the strongest associations being for bone and joint infections development of sepsis Likewise patients with HIV are prone to diabetes in younger people and in the absence of obesity 157 158 In this sense several hypotheses have been proposed to understand the mechanisms for this link including the effects of antiretroviral drugs ARVD lipodystrophy coinfections and autoimmunity Susceptibility to infections in persons with diabetes mellitus Patient education Diabetes and infections The Basics the magnitude of the effect of diabetes on the risk of infection remains an active research question Host and organismspecific factors that may explain why people with DM are more susceptible to particular infections will be reviewed here The clinical features diagnosis and Diabetes and Infections In addition diabetic patients are more susceptible to infection Several studies have reported the increased risk of lower respiratory tract infections such as pulmonary tuberculosis 36 and pneumonia 710 urinary tract infections 11 12 and skin and soft tissue infections 1315 in people with diabetes Diabetes Mellitus and Infection Endotext NCBI Bookshelf Several studies from different countries have reported that 1333 of patients with HCV infection have diabetes mostly type 2 diabetes mellitus T2DM compared with the prevalence of 410 for nonHCV control population These data suggest that patients with HCV are 3 times more likely to develop DM than individuals who are HCV negative Historically infections have been an important cause of death and morbidity in people with diabetes 1 2Although this remains the case particularly in low and middleincome countries where infections are commonly presenting features of previously undiagnosed diabetes infection has been an understudied complication of diabetesPeople with diabetes develop infections more often than Type 2 Diabetes and its Impact diabetes kaki melepuh berair hitam on the Immune System
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