why diabetes damage blood vessels - This diagram illustrates that in the del prato diabetes kidney normal state factors with protective functions in the vasculature can render blood vessels less susceptible to vascular disease and can counteract mechanisms which promote vascular injury Having diabetes means youre at much greater risk of developing foot problems But understanding how diabetes affects feet can help you avoid these complications Raised blood glucose levels also known as blood sugar can damage the sensation in your feet This can also affect your circulation which can lead to you getting less blood supply Diabetes and feet Foot problems Diabetes UK In diabetes the organs most at risk from blood vessel damage include the heart the brain the eyes the nerves and the kidneys Organ damage sustained as a result of high blood glucose levels is referred to as a diabetic complication Stopping the damage that diabetes causes to arteries and veins Both Type 1 and Type 2 diabetes cause high blood sugar The sugar also called glucose damages the inner linings of both big and small arteries The arteries respond by layering on plaque a substance that fills in the arteries so that oxygenrich blood has a hard time getting through to the eyes kidneys legs and feet Complications of diabetes Guide to diabetes Diabetes UK How blood vessel damage from high glucose concentrations Diabetic vascular diseases molecular mechanisms and Nature Effects of diabetes on the body and organs Medical News Today Diabetes and Vascular Disease Circulation AHAASA Journals How to improve blood circulation if you have type 2 diabetes Diabetic panvascular disease DPD is a clinical syndrome in which vessels of various sizes including macrovessels and microvessels in the cardiac cerebral renal ophthalmic and peripheral When you have diabetes high blood sugar for a period of time can damage your blood vessels This can sometimes lead to heart attacks and strokes Kidney problems nephropathy Diabetes can cause damage to your kidneys over a long period of time making it harder to clear extra fluid and waste from your body Diabetes can lead to blood vessel damage and raise your risk of heart disease blindness and limb amputation Weve been funding research to find ways to grow or repair blood vessels damaged by diabetes Mouse Study Reveals Mechanism behind Diabetes Blood Vessel Damage Diabetes puts you at high risk for conditions that affect your circulatory system including High blood glucose levels cause fatty deposits to form inside blood vessels Over time these deposits make your blood vessels narrow and hard lessening blood flow Common mechanisms underlying diabetic vascular complications Numerous studies have established the link between inadequately controlled blood glucose level and microvascular complications of diabetes such as renal and retinal symptoms However the relationship between elevated blood glucose and atherosclerosis of large arteries appears to be less straightforward The alterations in vascular homeostasis due to endothelial and smooth muscle cell dysfunction are the main features of diabetic vasculopathy favouring a proinflammatorythrombotic state which ultimately leads to atherothrombosis Diabetic neuropathy nerve damage Diabetes UK Elevated blood glucose levels can damage small and large blood vessels increasing the risk of microvascular diagnosa diabetes melitus menurut nanda complications such as diabetic neuropathy and nephropathy and macrovascular complications like PAD Vascular complications of diabetes mechanisms of injury and Diabetes mellitus substantially increases the risk of developing coronary cerebrovascular and peripheral arterial disease The pathophysiology of vascular disease in diabetes involves abnormalities in endothelial vascular smooth muscle cell and platelet function Part I of this review will focus on the most current advances in the pathophysiological mechanisms of vascular disease i emerging role of endothelium in obesityinduced insulin resistance ii hyperglycemiadependent microRNAs deregulation and impairment of vascular repair capacities iii alterations of coagulation platelet reactivity an A Comprehensive Review of the Vascular Consequences of The Diabetes MellitusAtherosclerosis Connection The Role of The main cause of the pathological changes is atherosclerosis of the large blood vessels of the lower extremities leading to blood circulation disorders One of the characteristic secondary pathological changes is diabetic foot Abstract Diabetic vascular complications DVCs including macro and micro angiopathy account for a high percentage of mortality in patients with diabetes mellitus DM Endothelial dysfunction is the initial and role step for the pathogenesis of DVCs Hyperglycemia and lipid metabolism disorders contribute to endothelial dysfunction via Diabetic retinopathy Symptoms causes Mayo Clinic Doctors departments On this page Overview Symptoms Causes Risk factors Complications Prevention Overview Diabetic retinopathy dieuhBETik retihNOPuhthee is a diabetes complication that affects eyes It39s caused by damage to the blood vessels of the lightsensitive tissue at the back of the eye retina Diabetes and vascular disease pathophysiology clinical A mechanism in the cells that line our blood vessels that helps them to process glucose becomes uncontrolled in diabetes and could be linked to the formation of blood clots and Blood Vessels Diabetes The Impact of Diabetes on Vascular Disease Progress from the Diabetes and peripheral artery disease A review PMC Neuropathy is one of the longterm complications of diabetes Over time high blood glucose levels also known as blood sugar levels can damage the small blood vessels that supply the nerves in your body This stops essential nutrients reaching the nerves This means the nerve fibres can become damaged and they may disappear Diabetes and vascular disease pathophysiology clinical Diabetes mellitus is not merely a disorder of carbohydrate metabolism but a cause of vascular disease affecting nearly all blood vessel types and sizes Indeed vascular complications are responsible for most of the morbidity hospitalizations and death that occur in patients with diabetes mellitus 1 Epidemiology Why diabetes can damage your blood vessels and how to know Keywords Diabetes Peripheral arterial disease Diabetic foot ulcers Lower limb complications Core Tip Peripheral arterial disease PAD is a major cause of nonhealing ulcers lower limb amputation and mortality especially in people with diabetes Excess blood sugar decreases the elasticity of blood vessels and causes them to narrow impeding blood flow This can lead to a reduced supply of blood and oxygen increasing the risk of Vascular Complications of Diabetes Circulation Research Diabetes contributes to large blood vessel damage associated with common cardiovascular problems such as stroke and heart disease but diabetes also deteriorates dr nyan 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