decompensated type 2 diabetes mellitus and hyperthyroidism - The Relationship between Type 2 Diabetes Mellitus and Related Thyroid

decompensated type 2 diabetes mellitus and hyperthyroidism - Thyroid Dysfunction and Type 2 Diabetes skripsi diabetes Mellitus Screening Springer The Relationship Between Type 2 Diabetes Mellitus and Related Thyroid The Relationship between Type 2 Diabetes Mellitus and Related Thyroid Thyroid Disorders and Diabetes Mellitus PMC PubMed Central PMC Thyroid dysfunction TD the most common endocrinal pathology next to diabetes mellitus DM is a condition characterized by an increased or decreased production of thyroid hormones TH TDs occur as hypothyroidism clinical or subclinical or hyperthyroidism clinical or subclinical and are reflected in circulating levels of free triiodothyronine FT3 free thyroxine FT4 and TSH Poudel et al described a case of an 84yearold woman with type 2 diabetes who developed apathetic hyperthyroidism due to Graves disease although without thyroid storm at presentation 6 A case of thyroid storm associated with Graves disease masked by diabetic ketoacidosis in a 59yearold woman was described by Osada et al The Relationship Between Type 2 Diabetes Mellitus and Related Cureus Diabetes mellitus DM and thyroid dysfunction TD often tend to coexist in patients Both hypothyroidism and hyperthyroidism are more common in type 2 diabetes mellitus T2DM patients than in their nondiabetic counterparts Current guidelines are neither clear nor specific about the frequency of thyroid function monitoring in T2DM patients Circulating thyroid hormones affect several Thyroid function and risk of type 2 diabetes a populationbased Association between thyroid dysfunction and type 2 diabetes a meta Diabetes and thyroid diseases are caused by endocrine dysfunction and both have been demonstrated to mutually impact each other Variation in thyroid hormone levels even within the normal range can trigger the onset of type 2 diabetes mellitus T2DM particularly in people with prediabetes However the available evidence is contradictory Thyroid disorders are also significantly more prevalent in type 2 diabetes mellitus T2DM patients ranging between 99 and 48 Furthermore studies have also recorded a high prevalence of thyroid disorder in the 134 diabetic population with a air tebu untuk diabetes higher prevalence 314 among females with type 2 diabetes than males with T2DM 69 2 Background Diabetes mellitus and thyroid disease are two areas of broad interest in the field of endocrinology and metabolism Variation of thyroid hormone concentration even within the normal range may portend the onset of type 2 diabetes mellitus T2DM especially among those with prediabetes However current evidence is mixed Methods Prospective studies which assessed diabetes Autoimmunity has been implicated to be the major cause of thyroiddysfunction associated diabetes mellitus 5 7 Unmanaged pro diabetes both type 1 and type 2 may induce a low T3 state characterized by low serum total and free T3 levels increase in reverse T3 rT3 but near normal serum T4 and TSH concentrations 8 Diabetes mellitus DM and thyroid dysfunction TD are the two most common endocrine disorders in clinical practice It is well known that Hashimotos thyroiditis and Graves disease are autoimmune disorders that constitute the most prevalent forms of TD 1 It is also known that type 1 DM occurs due to autoimmune destruction of Prevalence of thyroid dysfunction and associated factors among adult Diabetes and Hyperthyroidism Is There a Causal Link PMC Thyroid disorders remain the most frequent autoimmune disorders associated with type 1 diabetes This was shown in a crosssectional study involving 1419 children with type 1 diabetes mellitus where 35 had Hashimotos thyroiditis 11 In addition positive TPO antibodies have been reported in as high as 38 of diabetic individuals and have Diabetes mellitus and thyroid disease are the two most common endocrine disorders often coexisting in patients The role of autoimmunity has been wellrecognized in the link between autoimmune thyroid disease and type 1 diabetes mellitus A relation between thyroid dysfunction and type 2 diabetes mellitus has also been suggested but the possible underlying mechanisms and drivers show Type 2 Diabetes Decompensation as the diabetes without medication Clinical Presentation of Thyroid

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