diabetes dan osteoporosis - Association between type 2 diabetes and osteoporosis risk A

diabetes dan osteoporosis - Introduction Osteoporosis OP one of the alodokter berkaitan dengan diabetes most common metabolic skeletal disorders is characterized by decreased bone mass and increased destruction of bone microstructure which consequently increases bone fragility and fracture risk OP tends to occur in older people and individuals with predisposing health condition and has been considered as a serious public health concern Prevalence of osteoporosis in patients with diabetes mellitus a Osteoporosis Fractures and Diabetes PMC National Center for Investigations into the molecular link between diabetes and osteoporosis show that on the cellular level T1DM has been shown to hinder bone formation and even favor bone resorption Hamann et al 2012 This facilitates bone loss in these patients and puts them at an increased risk for negative outcomes in relation to bone health The incidence of osteoporosis in patients with diabetes is influenced by a number of factors such as the cooccurrence of obesity the type and duration of diabetes the presence of chronic complications as well as the type of therapy applied In type 2 diabetes increased body fat inhibits the expression of genes involved in osteoblastogenesis Diabetes mellitus DM is a pandemic and chronic metabolic disorder with substantial morbidity and mortality In addition osteoporosis OP is a silent disease with a harmful impact on morbidity and mortality Therefore this systematic review focuses on the relationship between OP and type 2 diabetes mellitus T2DM Diabetes can affect bones in several ways Both type 1 and type 2 diabetes can increase osteoclast function but decreases osteoblast function leading to accelerated bone loss osteopenia and Osteoporosis and Diabetes Osteoporosis and diabetes possible links and diagnostic difficulties Osteoporosis and type 2 diabetes mellitus what do we know and what we Abstract It is well established that osteoporosis and diabetes are prevalent diseases with significant associated morbidity and mortality top diabetes doctor in bhubaneswar Patients with diabetes mellitus have an increased risk of bone fractures In type 1 diabetes the risk is increased by 6 times and is due to low bone mass Despite increased bone mineral density BMD Type 2 Diabetes and Osteoporosis A Guide to Optimal Management Diabetes and bone health latest evidence and clinical implications Osteoporosis is clinically diagnosed using both the World Health Organization criteria based on BMD and the incidence of fragility fractures without Tscore data Although numerous studies have assessed the risk of fractures or BMD change only a few crosssectional studies have explored the composite risk of osteoporosis in diabetes Objectives In this review the authors aimed to clarify the relationship between the occurrence of osteoporosis and diabetes analyze the differences between the pathogenesis of osteoporosis in different types of diabetes and propose the most effective diagnostic strategy and fracture risk assessment in diabetic patients Material and methods A analysis of publications in MEDLINE COCHRANE How Do Diabetes and Osteoporosis Affect Each Other Healthline Type 2 diabetes T2D accounts for most people affected and its prevalence increases with age Osteoporosis affects 125 million people in Europe India Japan and the United States it is estimated that one in three women and one in five men over the age of 50 will experience an osteoporotic fracture at some point in life As the Association between type 2 diabetes and osteoporosis risk A Osteoporosis is a bone condition defined by low bone mass increased fragility decreased bone quality and an increased fracture risk1 It is the most prevalent metabolic bone disease in the United States Using World Health Organization WHO criteria the third National Health and Nutrition Examination Survey NHANES III 19881991 reported that 3450 of postmenopausal white women Treatment of Diabetes etika study untuk penyakit diabetes melitus and OsteoporosisA Reciprocal Risk

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